<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30042
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MDEPQQPSSLATAFPSPPPFWTSFTPSNIEQIASLRAAALSSAQAKASDASPKLPLRLLDLPAELRNLQPPEPPADGHYRCFGDQFWLDAPLPTLQELSIDQLYTPPASPSPSSSSITKPHHDRAFTLKRLAKSLLLNFLELVGIMAINPEHYVEKVDDLKTLFVNFHHLLNEYRPHQARESLILMMREQLERSRAETRGIREMKERVEGVLEGLAAKGVENLAVDVQMEEPVADRGREVWEELERQFGGVVT |
Length | 253 |
Position | Middle |
Organism | Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf spot fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes>
Helotiales> Dermateaceae> Marssonina.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.397 |
Instability index | 56.77 |
Isoelectric point | 5.24 |
Molecular weight | 28392.95 |
Publications | PubMed=22876864
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060
ECO:0000256 ARBA:ARBA00003669
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP30042
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 57.56| 15| 16| 187| 201| 1
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187- 201 (24.52/16.91) MREQLE..RSRAETRGI
204- 220 (16.59/ 9.17) MKERVEgvLEGLAAKGV
225- 237 (16.45/ 9.03) VDVQME..EPVAD.RG.
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 35.78| 10| 27| 133| 142| 2
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133- 142 (16.53/11.10) KSLLLNFLEL
161- 170 (19.25/13.95) KTLFVNFHHL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 136.48| 33| 92| 5| 39| 3
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7- 39 (57.81/27.66) PSSLATAFPSPPP...........FWTSFTPSNIEQIASLRAAA
62- 99 (32.72/ 9.26) PAELRNLQPPEPPadghyrcfgdqFWL...DAPLPTLQELS...
102- 132 (45.94/18.71) ..QLYTPPASPSP...........SSSSITKPHHDRAFTLKRLA
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