<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP30011

Description ATP-dependent DNA helicase Q1
SequenceMADQLASMMAKSTLPTDMSAPVKDFTTDPRHLVLLHGFQLEERAHSPAGDHVNIEKPAENTFSTQDSIASSMPSLPSPQQPQMSQPSPSQGISMQHSPAMPPMQQNPPQQQPQQQPMVSQPQVTNQMPPQSQYDPMKMQNMMPNDMQNRSTAMATNPINQPVFSQPTMDQQPNVNMPAQPGQPNPMKDRKIIWQGILEWQEKMKAGGPQTPKVNRQLQCHLSIGQADPDINAMNWPKVLIMQLIPQSLLNSTQLQPLFKNSRQVAFHFGSQNLDDLRNLYKVMGTGFAGCVHFPAGSQCEVRVLLLLFSNKRRAFIGLIPNDQTAFVNGIRSVIYSHKIRQQQQQQRPDQPPQMPQQTGFPGPQQTMPNQPVQNPQGAQFGVQQMPQVSMQNPMMTQQQANMIKQKSSEYKEAMDNIQQLIQRRFTNQSGIIYCLSRKESQDVTMDLQQRGIKTGCYHADLSGQERSRVVVATTAFGMGIDKPNVRFVIHYSVSKSMENLYQESGRAGRDNQKSHCIVYYRLADIFRQSCMVFTEQTGLDNLYGIMAYCTDLTRCRRSVIAQHFGESWDRSHCKEMCDHCQNPVETEKKNVKQICQQLIEILNQASGLEERLTAIKLMDAYQGKKVGGFRVSGLNLAPVTRDVLERIIALMLIKGYLREDFHFTAYTTISYLLPGDKRSLLKCDSTTVLLECIQRQKSTKDNSKHQSKTGLSKSEKQNSSTKPKLVIVKSQNSSEPGPSTEREKVSEKKKLPLKRKKPVIIDSDDSDLDFGEQSSESLVVKKRYIGHSPSSQENGENGVCSETNGVGNSVVDAIELDSDSND
Length822
PositionUnknown
OrganismCrassostrea gigas (Pacific oyster) (Crassostrea angulata)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Bivalvia> Autobranchia> Pteriomorphia> Ostreida> Ostreoidea> Ostreidae> Crassostrea.
Aromaticity0.05
Grand average of hydropathy-0.674
Instability index58.70
Isoelectric point8.79
Molecular weight92370.10
Publications
PubMed=22992520

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
helicase activity	GO:0004386	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP30011
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.33|      21|      25|     267|     291|       1
---------------------------------------------------------------------------
  267-  289 (36.67/30.54)	HFGSQNldDLRNLYKVMG..TGFAG
  532-  554 (30.66/26.85)	VFTEQT..GLDNLYGIMAycTDLTR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.54|      25|      25|     100|     124|       2
---------------------------------------------------------------------------
   78-  108 (38.83/14.68)	PQQPQmSQPSPSQG.ISmqhspaMPP......MQ..QN..P......P
  109-  144 (34.55/12.21)	QQQPQ.QQPMVSQPQVT....nqMPPqsqydpMK.mQNmmP......N
  353-  382 (28.16/ 8.52)	.QMPQ.QTGFPG.PQQT......MPN.......QpvQN..PqgaqfgV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.31|      20|      24|     390|     412|       4
---------------------------------------------------------------------------
  390-  412 (27.38/19.46)	MQNpMmtQQ..QANMIKQKSSEY....KE
  414-  439 (23.93/ 7.88)	MDN.I..QQliQRRFTNQSGIIYclsrKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.68|      19|      24|     176|     197|       5
---------------------------------------------------------------------------
  176-  197 (27.91/26.04)	MPAqPGQPNPMKDRKIiwQGIL
  203-  221 (34.78/18.53)	MKA.GGPQTPKVNRQL..QCHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.23|      21|      25|     756|     776|       6
---------------------------------------------------------------------------
  724-  742 (25.53/13.17)	.KLVIVKSQNSS.EPGPST..ER
  756-  776 (35.47/21.34)	KKPVIIDSDDSDLDFGEQS..SE
  781-  802 (30.23/17.04)	KKRYIGHSPSSQEN.GENGvcSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.73|      13|      27|     479|     491|      10
---------------------------------------------------------------------------
  479-  491 (23.79/15.52)	GIDKPNVRFVIHY
  508-  520 (24.94/16.63)	GRDNQKSHCIVYY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.22|      12|      34|     610|     621|      11
---------------------------------------------------------------------------
  610-  621 (20.55/14.84)	ERLTAIKLMDAY
  645-  656 (20.67/14.96)	ERIIALMLIKGY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP30011 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KIRQQQQQQRPDQPPQMPQQTGFPGPQQTMPNQPVQNPQGAQFGVQQMPQVSMQNPMMTQQQANMIKQKSSE
2) LVVKKRYIGHSPSSQENGENGVCSETNGVGNSVVDAIELDSDSND
3) MADQLASMMAKSTLPTDMSAPVKDFTTDPRHLVLLHGFQLEERAHSPAGDHVNIEKPAENTFSTQDSIASSMPSLPSPQQPQMSQPSPSQGISMQHSPAMPPMQQNPPQQQPQQQPMVSQPQVTNQMPPQSQYDPMKMQNMMPNDMQNRSTAMATNPINQPVFSQPTMDQQPNVNMPAQPGQPNPMKDRKIIW
4) TKDNSKHQSKTGLSKSEKQNSSTKPKLVIVKSQNSSEPGPSTEREKVSEKKKLPLKRKKP
338
778
1
699
409
822
193
758










Molecular Recognition Features






MoRF SequenceStartStop




1) FGEQSSESLVVKKRYIGHSPS
2) RKIIWQGILE
3) SEKKKLPLKRKKPVIID
770
189
746
790
198
762