<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29997

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMRAWRERWSDHQWGVHLKSVVNSCNGDSKELPEILLQQALVGPNPNALIIGYLQHIVLSQMIPPCSALNLIQKYDDISKPYCTIGLIELTDAIACNISVTSGMESSVVLCKCLQKTLHWLMMCILQSMKAMKDSQQQQEYISIIDAASVAALHIADNTTVQALLYVAMSEDQDNFRDYEQAVINVRGTLSQPVVQDMALPSQPLCEVSHLGICPTINTLVTLEAVLNPSSDVQPFIDQLCVSERLLHLPRPSLYCEILRACFMGLNNCADTPEELKWAAFTYLKLPQALRYMKQQSPNQDIGEDLYQGLSELMNSVPLLDLVEIKLKCECLKFLIGEFSKNDLLDKAQTQQLMNRRSADCGTKIETSNHASPIQIIRNEQQLPKIIKTLDNADASKTPSDMMSLLCLLTSGRNLDFILAVASSTGKLLGLASKLVKINEFAKQTQGEMGKMAQTRIMLFDISFLMLCHISQVYGLEIIAPSPEYSDSFFAHWATRCLPEDGKYKCIDNFTPTDQGKVDLLIQHLISGVDVNKLNITRMNEYCLNFPLALQEILIAWEHGAVSADSIKMIMEHIKNKMCCIPIVLCAWLCSYISMIPDKAREKPLQMIQMLQTPAMNPDPDLNYNERYALMTPILHKLINDILPVSKRVNYINYVPSDKLPSEVMDECIKGVFRRGWLDMKSVQTLEYLLNLCGSDWFCDRCIEAMLESSRLEDLMKALSLVFAIFHMDLEHITLSLLFHTLPRLLQTTGYHNLLSDPRGNTLAKLSVMILVSAQNSKNAEKDTIPHLRRGRKRSRKEVELEDMEETECRPVKRSKSSSLEPQLTLDSEGFNFDFLTAKEDGETSPTFDTKDPLNKSLANLMRLMNALSQDSQVSPRMSFIINFVREAINCGSQNAKFTLQFMPPQMVSNLLKSVQGVFNNRHILQICDLSTSIGRKVATQAICQNSRLQGPANSAKTGTVNST
Length963
PositionTail
OrganismCrassostrea gigas (Pacific oyster) (Crassostrea angulata)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Bivalvia> Autobranchia> Pteriomorphia> Ostreida> Ostreoidea> Ostreidae> Crassostrea.
Aromaticity0.06
Grand average of hydropathy-0.093
Instability index50.55
Isoelectric point5.92
Molecular weight108300.59
Publications
PubMed=22992520

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29997
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.52|      40|     343|     499|     545|       3
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  437-  477 (65.35/35.73)	INEFAKQTQGEMGKMAQTRIMLFDISFLMLCHISQvYGLEI
  506-  545 (69.17/32.41)	IDNFTPTDQGKVDLLIQHLISGVDVNKLNITRMNE.YCLNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     172.57|      56|     571|      13|      72|       4
---------------------------------------------------------------------------
   13-   72 (89.48/66.66)	WgvhLKSVVNSCNGDSKELP.EI..LLQQALVGPNPN.......ALIIGYLqHIVLSQMIPPCSALNLIQ
  587-  652 (83.08/49.98)	W...LCSYISMIPDKAREKPlQMiqMLQTPAMNPDPDlnyneryALMTPIL.HKLINDILPVSKRVNYIN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29997 with Med24 domain of Kingdom Metazoa
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