<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29995

Description Cell division protein kinase 8
SequenceMDYDFKRQKAAERQKVEDLFDFEGCKVGRGTYGHVYKAKRKDGSESKEYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHQDRKVWLLFDYAEHDLWHIIKFHRSAKANKKQIDVPRNMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGTERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTYEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPLEKDWEDIRKMPEHSTLTKDFKRSNYLNCTLVKYMEKHKIKADSRQFHLLQKLLTMDPTKRITSDYAMKDPYFTEEPHPSQDIFEGKPIPYPKREFLTDEDDDKADTGASKATDQSSNHTQPAKRVRVMPPSTTSTSASMSGSLHVSVVRSSSHWPTPPGGGTWSASYDEM
Length433
PositionKinase
OrganismCrassostrea gigas (Pacific oyster) (Crassostrea angulata)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Bivalvia> Autobranchia> Pteriomorphia> Ostreida> Ostreoidea> Ostreidae> Crassostrea.
Aromaticity0.10
Grand average of hydropathy-0.607
Instability index48.33
Isoelectric point8.67
Molecular weight50001.54
Publications
PubMed=22992520

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process
cell division	GO:0051301	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29995
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     205.29|      63|     130|     108|     173|       1
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  108-  173 (97.99/79.15)	IKfhRSAKANKKQIDVPRNMVKSLLYQILDGIHYLHANWVLHRDLKPANIL..VMGEGTERGRVKiAD
  241-  305 (107.30/74.31)	IK..TSNPYHHDQLDRIFNVMGFPLEKDWEDIRKMPEHSTLTKDFKRSNYLncTLVKYMEKHKIK.AD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29995 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DYAMKDPYFTEEPHPSQDIFEGKPIPYPKREFLTDEDDDKADTGASKATDQSSNHTQPAKRVRVMPPSTTSTSASMSGSLHVSVVRSSSHWPTPPGGGTWSASYDEM
327
433










Molecular Recognition Features






MoRF SequenceStartStop




1) WSASYD
2) YDFKRQK
426
3
431
9