<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29985

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMSQKSIEDTIIDVVRDILHGEAIEAALCSVILHTEESLQWKKEHCFNSLKTALANVPQESLDTALKCYITQIYNVQNASRVELLLDLLEGLVEYNVVPAKPICDALLDHELLSYNASLMWTKTFQLMRKIIGGVDYKGCRDLLRGILEKCQGIKEDENVSVMPDIDTPVNLVAHILDRNVCLLPAYLAVNEINKVCPEDRKWPHWKMGNILADFVHSFRPAAQMVTVSGRTHLLPVVGYSIAISTSNVWRLSSSCLKFPLNGPLPYDKELSEPQTGLLRYVLEQPYSRDMVCNMLGLNKQWSRSYGAPTACNCVSTEFYLAIHCALAESPPRAHGVLGDFTARPRRALRADCVHKTFSSSCHFSSFRGLDDNVVETPWERGINAEKTSRERNERSNSSLGSLCERSQMESNLFKRCGCAVRARKRRSGIPKDSVKSLCKRNRLITASTLRLAAFLERADGALVALLEILWRCHGDLTTLLWRVYQNAEPRRVLCACSKCAPSHGVLQCSRRSHCDGRRCRCVLTAL
Length526
PositionTail
OrganismCrassostrea gigas (Pacific oyster) (Crassostrea angulata)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Bivalvia> Autobranchia> Pteriomorphia> Ostreida> Ostreoidea> Ostreidae> Crassostrea.
Aromaticity0.06
Grand average of hydropathy-0.167
Instability index52.69
Isoelectric point8.65
Molecular weight59107.69
Publications
PubMed=22992520

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29985
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.55|      14|      19|      73|      91|       1
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   73-   86 (24.38/25.86)	YNVQNASRV.ELLLD
   94-  108 (21.17/ 7.81)	YNVVPAKPIcDALLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      66.46|      16|     143|     325|     352|       2
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  325-  340 (29.93/ 7.34)	ALAESPPRAHGVLGDF
  464-  479 (29.30/ 6.93)	ALLEILWRCHGDLTTL
  498-  506 ( 7.23/13.78)	...KCAP.SHGVL...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.45|      10|     143|     342|     352|       3
---------------------------------------------------------------------------
  342-  352 (16.04/12.93)	ARPRRALRAdC
  487-  496 (21.41/12.00)	AEPRRVLCA.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.92|      15|     104|     403|     422|       5
---------------------------------------------------------------------------
  405-  422 (23.42/24.39)	RSQMESnlfKRCGCAVRA
  511-  525 (30.51/13.39)	RSHCDG...RRCRCVLTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.41|      11|      20|      35|      46|      13
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   35-   46 (15.86/15.77)	EESLQwKKEHCF
   58-   68 (19.55/11.55)	QESLD.TALKCY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29985 with Med23 domain of Kingdom Metazoa
Unable to open file!