<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29979

Description Mediator of RNA polymerase II transcription subunit 28
SequenceMNPLHTCKLSDSLTFHLDRKETNKQYEPKCSSNEKGQKMAAVKDVKPQSPHLIDELEESFQNCIESLTSQEYFNVQDYDEVKTGMELSLQKFLELARQTEAFFLKKRLILSKQKPEQFIKDETEDLRAELERKDIMIKKHQERLQKWQAMLNSVNKGSFYSSQAQQQMSGPSGGQQYNPHAVPPGPFTGSGGMPGQTHMGLSSSAMSGGQFSQTLPQQSPHMMMSRQGPTPHQQQPPPYNTQGPLQYLEQSMSNIGQSLSRP
Length262
PositionHead
OrganismCrassostrea gigas (Pacific oyster) (Crassostrea angulata)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Bivalvia> Autobranchia> Pteriomorphia> Ostreida> Ostreoidea> Ostreidae> Crassostrea.
Aromaticity0.07
Grand average of hydropathy-0.930
Instability index71.35
Isoelectric point7.09
Molecular weight29666.11
Publications
PubMed=22992520

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29979
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      61.81|      14|      15|     190|     203|       1
---------------------------------------------------------------------------
  180-  197 (18.95/ 7.47)	HaVPPGPftgSGGMPGQT
  198-  214 (21.25/ 9.26)	H.MGLSSsamSGGQFSQT
  221-  233 (21.60/ 9.54)	H.MMMSR...QGPTPHQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.07|      26|      34|      16|      44|       2
---------------------------------------------------------------------------
   16-   44 (39.72/34.14)	HL.DRKETNKQyepKCSSNEKGQKMAAVKD
   51-   77 (41.35/25.94)	HLiDELEESFQ...NCIESLTSQEYFNVQD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29979 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SFYSSQAQQQMSGPSGGQQYNPHAVPPGPFTGSGGMPGQTHMGLSSSAMSGGQFSQTLPQQSPHMMMSRQGPTPHQQQPPPYNTQGPLQYLEQSMSNIGQSLSRP
158
262










Molecular Recognition Features






MoRF SequenceStartStop




NANANA