<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29967

Description ATP-dependent RNA helicase
SequenceMFATRFDPNILIVDEQKTSSKRKLSDVESDNEDENKNESSDSDEEMKDSSDSGSDSDSSEGSDSESDSSSDSDDDSENDSSDSETNGDDNEDNIKEDDNDKIIPDEKPTSEPLQPLEPQDHDSKFSNIISRFTTSVSKTEKLQSQQSEDQIDEDEDIKDAETHELGPLPQPELPRDQRLSRSQTNNSLNWLATPEYIKTDEIKPFKDFEISPIILKNLKDLGFDNAFATQIKTLGLLLPEINNKLNPNSIKGDLLVNASTGSGKTLAYTIPIIQSLQNRIVPRLRCIILVPTKPLINQVYKTMDSISKGIDLNIVTLGKSDLNLQDEHLKLIKNVPDIIISTPGRLVDHLNLKSIDLKNLQWCVIDEADRLLNQSFQDWSNVLITKLNDVNKGNNISKIFKPNLIKMIFSATLTTDSGKLSNLNFHNPRLIIVNNEESILQNDKIFTLPTQLSEHTIKLSSNSSSHKPLYLLKLFEWLKYPHNVLIFTKSNESTLRLSRLLSILVSKLSIPLIISNINSSQSRSEKSKLLKQFSEGSIHILISTDLISRGIDILTIQHVINYDLPNSSREYVHRVGRTARANNKGDAYNFLIGKGEVKFWNKINLDINRNEELNEIELEKVKDMEQVYVESLGELEKEVFNK
Length642
PositionKinase
OrganismWickerhamomyces ciferrii (strain F-60-10 / ATCC 14091 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031) (Yeast) (Pichia ciferrii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Phaffomycetaceae> Wickerhamomyces.
Aromaticity0.05
Grand average of hydropathy-0.611
Instability index46.83
Isoelectric point4.85
Molecular weight72561.31
Publications
PubMed=23193139

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
helicase activity	GO:0004386	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29967
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     197.56|      51|      54|      63|     115|       1
---------------------------------------------------------------------------
   25-   60 (40.11/15.90)	...SDVESDNEDENKN.....ESSDSDEE...MKDSSDSGSDSDSSE.................
   64-  115 (73.93/44.64)	.SESDSSSDSDDDSEN.....DSSDSETN...GDDNEDNIKEDDNDKiIPDEKpTSE..PL.QP
  120-  171 (50.66/22.74)	DHDSKFS........NiisrfTTSVSKTEklqSQQSEDQIDEDED...IKDAE.THElgPLpQP
  174-  201 (32.86/11.54)	PRDQRLSRSQTNNSLN.....WLATPEY...........IKTDE....................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     255.31|      55|      55|     419|     473|       2
---------------------------------------------------------------------------
  356-  406 (65.16/40.90)	DLKNLQW.....CVIDEADRLLNqsfQDWSNV.LITKLND.VN..KGNNISKIFKP.NLIK
  419-  473 (88.87/58.96)	KLSNLNFHNPRLIIVNNEESILQ...NDKIFT.LPTQLSEHTI..KLSSNSSSHKPLYLLK
  479-  531 (61.14/37.84)	KYP....HNV.LIFTKSNESTLR...LSRLLSiLVSKLSIPLIisNINSSQSRSEKSKLLK
  533-  570 (40.15/21.85)	......FSEGSIHILISTDLISR...GIDILT.I.....QHVI..NYDLPNSSRE......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.25|      43|      55|     239|     293|       3
---------------------------------------------------------------------------
  239-  284 (66.57/61.27)	PEINNKLNP.NSI............KGDLlvNASTGSGKtLAYTIP.IIQSLQNRIVPRL
  294-  350 (57.69/27.89)	PLINQVYKTmDSIskgidlnivtlgKSDL..NLQDEHLK.LIKNVPdIIISTPGRLVDHL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29967 with Med13 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MFATRFDPNILIVDEQKTSSKRKLSDVESDNEDENKNESSDSDEEMKDSSDSGSDSDSSEGSDSESDSSSDSDDDSENDSSDSETNGDDNEDNIKEDDNDKIIPDEKPTSEPLQPLEPQDHDSKFSNIISRF
2) TSVSKTEKLQSQQSEDQIDEDEDIKDAETHELGPLPQPELPRDQRLSRSQTN
1
134
132
185










Molecular Recognition Features






MoRF SequenceStartStop




1) DSDEEMKDSSDSGSDSDSSEGSDSESDSSSDSDDDSE
2) IIPDEK
3) MFATRFDPNILIVDE
4) SSDSET
41
102
1
80
77
107
15
85