<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29957

Description Serine/threonine-protein kinase
SequenceMYPNQSRQHQNTTQLQREYLLRLQQQQQSQQNGTGALMSAQQRKQSAQFQHLQQLQQQQQQQLNLSNSSNLSSSNPNPNYPNQQQNMYQNRPALMASNNCFTLLPYKTRKDALRKSVLQKYDIVGYIASGTYGRVYKAKSKNPKNSSGIFAIKKFKADKEGEVVYYTGISQSASREMALCRELNNNNITKLTETILENKCIYMVFEYAEHDLLQIIHFHSHPDTKSIPEQTVKSIMWQVLNGVSYLHQNWVLHRDLKPANIMVTSEGVVKIGDLGLARKFNNPLQSLYNGDKVVVTIWYRAPELLLGGRHYTPAIDLWAVGCILAELLALRPIFKGEEAKMDNKKNVPFQKNQMQKIVEILGTPSKEKWPSLPKYPEYPSLQQFKQFPNNLQAWYQSIGAQKKKGLQLLSSLLEYDPGKRMTAFDALLHPYFLETPLVSQNIFEGQQFKYPLRRIQTDDSDITSSAPSNKRGLNNDHDPLHSRKRQK
Length487
PositionKinase
OrganismWickerhamomyces ciferrii (strain F-60-10 / ATCC 14091 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031) (Yeast) (Pichia ciferrii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Phaffomycetaceae> Wickerhamomyces.
Aromaticity0.09
Grand average of hydropathy-0.707
Instability index52.20
Isoelectric point9.60
Molecular weight56036.18
Publications
PubMed=23193139

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IEA:UniProtKB-EC

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29957
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.99|      24|      31|       7|      37|       1
---------------------------------------------------------------------------
    7-   32 (39.16/18.82)	RQHQNTTQLQreYLLRLQQQQQSQQN
   41-   64 (42.83/21.33)	QQRKQSAQFQ..HLQQLQQQQQQQLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.32|      27|      54|     350|     379|       4
---------------------------------------------------------------------------
  352-  378 (49.15/37.16)	NQMQKIVEILGTPSKEKWPSLPKYPEY
  389-  415 (45.17/21.57)	NNLQAWYQSIGAQKKKGLQLLSSLLEY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29957 with CDK8 domain of Kingdom Fungi
Unable to open file!