<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29938

Description Uncharacterized protein
SequenceMGFSYEKRPLKRPRLGPPDVYPQEPKQKEDELTTVNVKHGFTTSLTISDEHQHGTARNYNITASKIGAFFNAIINKKEELNTLVDTGRKRLQINPKDNFWPATARSKTTVEAWFKDLAGFKPLNILSKKAPNFNKKEEIFMLLCEYNVPLIRATWFIKLSSAYTIAVSEAKIKSKRQLPDPTLEWTSTLLKFTKEQLTKLQDYYQNANMSMSSSHYLSMSEEQKISLKQWNYCTSLIKYMYQEGLLDRQEVLQWILDMLERYKSSSNSEDGLLKVLSPLALQYCSEFCQSELLSRKLVYFCSRKLNTICNSVIDLNPPQSPTSKGASNNSVPSNTSSATNAASTLNDMMSCPHHRDILLPLSCIIQVILLECPTSLIWNHSGGGKLPSVLNGSPLDYLPCSPVVLPMPQRTNNIPLRKQLKQAEEIVKIRSQAAEGRWCLDKFHKSSIGAKTIKILNVLDALDRHSFERIDQNNSLDTLYNKIFLPPNSKDNSNPLLGNISMSTENETLKDNRSEYNVEQDQIVVKVLCEWALSSLRRGEHRGMAVARLLDKRQAEITGRESDSSVEVVPGGPSEDKDSIVSTPATLPLFQPLLMNFLDHDAPVLENTSTSRTTFTNLVHVFTELIRNDVFSHDAYMCTLISRGDLQSTNNIGMCQPGSNKPADTPSGAGPSQAQVHMEDDNLFDLKPNVPEHHNRHMDYDDSKIDDDLDKLLQHIKEEQQNSMDAPDSPKVEPFAGSSIGGLESNDPSTNTNDNMYKCRPSRHLLYATHFPLPLDEETTSHDCNQRHVLLYGFGKMRDDARHTIKRISKDICKLFSKKFSIDIAEGGKVKKHSRNEFNFEATTARVQNLSYFDQHVVTWQCSLNVLEAINAFATGNSNYLPVQEHVAFLFDLMELALNVNSLLDVCIQILMDIPDVEAQLAAKGSSLVRIYTTSLVLYIVGVLRRYHCCLLLNQEQVVGAFENLYRVVKHVSNPADCSSVERCVLSHLYDLYISAAPLLKGRLPGAEPFNTLYTKIRQTLHANLQPSTMTHGNWNSSYMNDLIMTYRRGCKIDPGWHRQLNESQSNRYSLVCNVVIAVATETSDIERLNDLAILSAELTASCSSLASEWLGVLMALCCSSNNPIIFGEVLSRVDMNDITVHNSLALFTSILVARHCFSLEDFVVHVALPSLLTVSNEGHGAADTDPEAEASARLTCHLLLRLFKTTEVPQPSLYSVGTSPNPISNSNSSCSIKQSCDRHLLAAAHNNIRVGPLLAVLKAIIVVGDATAQRPNQSIKKSPSSQVSTPGGTSKMPSELSISHILGTSDILGGSADHLLMELGGLGNADTQAPGLSDLAQFVLREICSQEWVLERCLQNPEELCHQDMLLDSMLSSKQAQRLLHMICYPETASGSDISLDSRTIITNILENSDQWTLRMSWLEMQLMFKQFSPNSPDLNQWLDIVAKAAIDMFQHNLNTQNKSENIKKTHSMWLLAPLISKLPSAVQGRVLKVAGQVLESGNMIGLGGSNSGNVTPITTHGVSGGGSSSRSSNKGTPPHPRPSQNTNSVPSPPAILAYHQPFLSLVLSCLKGQDDQRENLLSSVHNQLSQYLVLSKEERLGIQEGCASNKEVDAAQDSLALRFSLVGGMFDTIQRSTALTIDWAVLFVQLVTYSVIDLTNNTKLFNTVIDMLATLIHSTLVSDSQTEKGEENRKHYQNLIKKLKKEVGEKHSMSISQVRQLLPLGKQQCEIITCEQIGTDIKGNKISTGLDSNDKQGLKVCDKQRVSAWDLLEGHKNPAPLSWSWFSAVRVERKPLWYEENHRMLKFHTHSLVKSASYFLEPLPLPPEDLEPPQEKPIKGVGSGMNMGSGPGRPDTPSSVPESPGRGVKRNMKAQGGPPNPRRKKQQQPPPMSPMTPNAQMGPGPQMHPQMQNTQGQHMGYSGGMFPMQPGPGPVPGAGPVPVPGPAPGPSPAQNPQWNSYGQQAPQGGTNFYPQQVPPTPVPGPGTRFDRPGNTSKQALSHMLRMRLPTNQYMGQTGQQPNMNPNFQPMPRQQFIRRGQNNVPIPPPQQNTPQMYPTQQPTQMYSNMQQSMNQNYGGYVGQQPGMRPPYMQNQNVPMNPMSGPQNPAPPYTRPTGPNQQAPHSQYHQVNIVNKIQLCNVNIYLIYPINLVSKTI
Length2153
PositionKinase
OrganismAcyrthosiphon pisum (Pea aphid)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Sternorrhyncha> Aphidomorpha> Aphidoidea> Aphididae> Macrosiphini> Acyrthosiphon.
Aromaticity0.06
Grand average of hydropathy-0.429
Instability index49.44
Isoelectric point7.43
Molecular weight239264.58
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29938
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     331.06|      49|      50|    1895|    1943|       1
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 1820- 1863 (64.27/28.03)	....PL.PL..............PPEDLEP.PQE.KP............IKGVGS.....GMNMG...SG.PGRPDTPSSVPeSPG
 1873- 1935 (97.18/46.74)	QGGPPN.PRrkkqqqpppmspmtPNAQMGPGPQM.HP............QMQNTQ.....GQHMG..YSG.GMFPMQPGPGP.VPG
 1936- 1982 (78.58/36.16)	AGPVPV.P................GPAPGPSPAQ.NP............QW.NSY.....GQQAP..QGGtNFYPQQVPPTP.VPG
 1983- 2030 (38.01/13.10)	.............................PGTRFdRPgntskqalshmlRMRLPT.....NQYMG..QTG.QQPNMNPNFQP.MPR
 2031- 2087 (53.02/21.64)	QQFIRRgQN.........nvpipPPQQ..NTPQM.YP............TQQPTQmysnmQQSMNqnY.G.GYVGQQPGMRP..P.
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.58|      17|      21|    1288|    1307|       2
---------------------------------------------------------------------------
 1288- 1307 (24.57/20.49)	GGTSKMPSELSishILGTSD
 1311- 1327 (30.01/16.14)	GSADHLLMELG...GLGNAD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     191.88|      59|     181|    1005|    1091|       3
---------------------------------------------------------------------------
 1026- 1091 (96.90/79.20)	QPSTMTHGNWNSSYMNDlimtyRRGCKIDPGWHRQLNESQSNRYSL.....VCNVVIAVATETSdiERLND
 1211- 1274 (94.98/37.41)	QPSLYSVGTSPNPISNS.....NSSCSIKQSCDRHLLAAAHNNIRVgpllaVLKAIIVVGDATA..QRPNQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.01|      25|     181|     253|     279|       4
---------------------------------------------------------------------------
  253-  279 (39.53/25.68)	QWILDMLerYKSSSNSED.GLLKVLSPL
  437-  462 (40.48/20.73)	RWCLDKF..HKSSIGAKTiKILNVLDAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.47|      17|      50|     231|     251|       5
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  231-  251 (25.02/25.90)	NYCTSLIkymyQEGLLDRQEV
  282-  298 (31.45/18.94)	QYCSEFC....QSELLSRKLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.11|      28|      51|     321|     351|       6
---------------------------------------------------------------------------
  321-  351 (37.11/31.12)	PTSKgASNNSVPSNTSSATNaASTLnDMMSC
  373-  400 (54.99/30.44)	PTSL.IWNHSGGGKLPSVLN.GSPL.DYLPC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.92|      36|      51|     923|     966|       7
---------------------------------------------------------------------------
  923-  966 (51.21/56.88)	AKGSSLVRIYTTSLV.LYIVGVlrryhcCLLlnQEQVVGA..FENLY
  976- 1014 (56.72/38.29)	ADCSSVERCVLSHLYdLYISAA......PLL..KGRLPGAepFNTLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.51|      18|     187|    1353|    1379|      11
---------------------------------------------------------------------------
 1353- 1370 (34.35/32.51)	RCLQNPEELCHQDMLLDS
 1382- 1399 (33.15/12.63)	HMICYPETASGSDISLDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.37|      15|      45|    1621|    1635|      12
---------------------------------------------------------------------------
 1621- 1635 (27.15/20.89)	FSLVGGMFDTIQRST
 1663- 1677 (26.22/19.88)	FNTVIDMLATLIHST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.17|      19|      45|    1524|    1542|      13
---------------------------------------------------------------------------
 1524- 1542 (32.73/15.63)	GSSSRSSNKGTPPHPRP..SQ
 1543- 1563 (24.34/ 9.56)	NTNSVPSPPAILAYHQPflSL
 1570- 1588 (28.11/12.29)	GQDDQRENLLSSVHNQL..SQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     144.32|      53|     339|     464|     551|      14
---------------------------------------------------------------------------
  463-  519 (75.03/51.77)	DRHSFErIDQNNSlDTLYNKIFLPPNSKDNSNPL....LGNISMSTENETLKdNRSEyNVE
  551-  576 (30.19/53.29)	DKRQAE.ITGRES.DSSVEVVPGGP.SED................................
 1431- 1465 (39.11/ 9.70)	........................PNSPDLNQWLdivaKAAIDMFQHNLNTQ.NKSE.NIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.78|      32|      52|    1092|    1123|      15
---------------------------------------------------------------------------
 1092- 1123 (56.02/41.07)	LAILSAELTA.SCSSLASEWLGV.LMALCCSSNN
 1145- 1178 (45.76/31.97)	LALFTSILVArHCFSLEDFVVHVaLPSLLTVSNE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.86|      24|      24|     680|     703|      19
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  671-  690 (29.61/13.80)	PSQAQVHM...........................eDDNLFDLKPNV
  691-  716 (40.23/21.38)	PEHHNRHMDYDDS.....................kiDDDLDKLLQHI
  717-  761 (23.03/ 9.09)	KEEQQNSMDAPDSpkvepfagssigglesndpstntNDNMYKCRP..
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29938 with Med12 domain of Kingdom Metazoa
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