<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29935

Description Uncharacterized protein
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
Length505
PositionKinase
OrganismAcyrthosiphon pisum (Pea aphid)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Sternorrhyncha> Aphidomorpha> Aphidoidea> Aphididae> Macrosiphini> Acyrthosiphon.
Aromaticity0.08
Grand average of hydropathy-1.131
Instability index68.72
Isoelectric point8.65
Molecular weight59840.60
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29935
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.84|      15|      16|     417|     431|       1
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  386-  400 (33.99/ 7.52)	QQQQQQQQQQQQQQQ
  417-  431 (35.65/ 8.22)	QQQQSQHPQQQQQQP
  435-  449 (37.21/ 8.89)	QQQQPQHPQQQQQQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     123.54|      31|      36|     135|     165|       3
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  102-  127 (25.64/12.85)	.........HDLWhiiKFH..RAAKANKKPVMVPKGM
  135-  165 (57.32/36.42)	ILD.GIHYLHSNW...VLH..RDLKPANILVMGEGPE
  171-  203 (40.57/23.96)	IADmGFARLF.NA...PLKplADLDPVVVTFWYRAPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.63|      15|      15|     454|     468|       5
---------------------------------------------------------------------------
  454-  468 (30.69/11.11)	QQPQQQHQQQPQHQQ
  472-  486 (30.94/11.28)	QQHQQDFHHVPQHQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     141.92|      31|      35|     279|     309|       6
---------------------------------------------------------------------------
  239-  267 (39.53/22.91)	..EDIKTSNpYHHDQLDRIFNVMGF.PQEKDW
  279-  309 (53.52/33.57)	LMKDFKRSN.YSNCSLVKYMDRHKIKPDSKAF
  317-  346 (48.87/30.03)	LMDPNKRIT.SEQAKQDSYFQEDP.TPTSDVF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29935 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAKQDSYFQEDPTPTSDVFAGCPIPYPKREFLTDDDQDDKDKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQ
2) QQQQVQQQQSQHPQQQQQQPPQQQQQQPQHPQQQQQQPQQQHQQPQQQHQQQPQHQQQPQQQHQQDFHHVPQHQQMMYSQVNPNGPGPNYSQRF
320
412
404
505










Molecular Recognition Features






MoRF SequenceStartStop




1) NYSQRF
500
505