<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29914

Description Uncharacterized protein
SequenceMQKTFFDIKHRLLSALDDEYNVTDMSTVFEVISTLEQLPVTTEVLEATRIGKMVNELRRKTLDKQLAKRAKELVQRWRNLMINSAQVIQQAKLPSSQPNGMLSNHSKRPMTSPDQCTAPLKKPKLNGMPSLSSAIMSPPVQKTPEPVPSPVNEPDPEPDPILEPQGPKKRGRKKGGKNSSKLGIKPTNPVDLERMVSVGASKLKTTQEIIASLRKDDENYQLEEKPQIPVQEFQDEPSITKVDKPSRPKVADIDRQIQEIYNRLPPLDLEAIDWSSPPPSPPRPPLSPTDLVDRAQIEGVTGNWENSETFREWHEVLTRANDTGEPLVILPYVIID
Length336
PositionUnknown
OrganismAcyrthosiphon pisum (Pea aphid)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Paraneoptera> Hemiptera> Sternorrhyncha> Aphidomorpha> Aphidoidea> Aphididae> Macrosiphini> Acyrthosiphon.
Aromaticity0.04
Grand average of hydropathy-0.713
Instability index54.93
Isoelectric point6.40
Molecular weight37786.76
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP29914
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     177.14|      37|      38|     223|     260|       1
---------------------------------------------------------------------------
  145-  168 (34.30/ 9.05)	EPVPS.PVNEPDPEPD....PILEPQGPK..............
  185-  218 (35.42/11.70)	..KPTNPV.DLERMVSVgaSKL.KTTQEIIA..S.L.R.KDDE
  223-  259 (64.03/24.47)	EEKPQIPVQEFQDEPSI..TKVDKPSRPKVA..D.IDR.QIQE
  262-  299 (43.39/14.48)	NRLPPLDLEAI.DWSS....PPPSPPRPPLSptDlVDRaQIEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.22|      17|      33|      93|     109|       2
---------------------------------------------------------------------------
   93-  109 (31.46/18.17)	LPSSQPNGMLSNHSKRP
  128-  144 (30.77/17.61)	MPSLSSAIMSPPVQKTP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP29914 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AQVIQQAKLPSSQPNGMLSNHSKRPMTSPDQCTAPLKKPKLNGMPSLSSAIMSPPVQKTPEPVPSPVNEPDPEPDPILEPQGPKKRGRKKGGKNSSKLGIKPTNPVDLERMVSVGASKLKTTQEIIASLRKDDENYQLEEKPQIPVQEFQDEPSITKVDKPSRPKVADIDRQI
2) DLEAIDWSSPPPSPPRPPLSPTDLVDRAQIEGVT
85
268
257
301

Molecular Recognition Features

MoRF SequenceStartStop
1) IDRQIQEIYNRLPPLDLEA
253
271