<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29902

Description Uncharacterized protein
SequenceMSLKELVPNGTKLADLEKRMVEDTMVRDGLVVGLRQVREEILPIRLKFNAFLNKMSHLDSEPQGAKTNEERFKEVRDNLLDLYKSIQTLSARFHEIQPLFSVIEQFGAVDGEKQFCPLETLGNGPTVSSIPTTVPTAPVGKKSAVSTPANNDKPSPSVGPTASSAAAKKPRKPRQSKKTPVHTPAGNPTPRTAAQTPLSVPSSSGPGGDVGVSSGAAAAAAASAMNSTISMPQHILSSAMSPMMGSTMGTPNNMNQMSSSQQPQAPQQQQQQVHAPFMGANPAASTNNTSAQSLTPANILSMNNGNMNATNAERPERYGSVDLSSMDLGNLDLGSLNMDFL
Length341
PositionTail
OrganismKazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBRC 10181 / NCYC 3082) (Yeast) (Saccharomyces naganishii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Kazachstania.
Aromaticity0.03
Grand average of hydropathy-0.455
Instability index48.26
Isoelectric point8.61
Molecular weight36077.35
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
RNA polymerase II activating transcription factor binding	GO:0001102	IEA:EnsemblFungi
RNA polymerase II core promoter sequence-specific DNA binding	GO:0000979	IEA:EnsemblFungi
RNA polymerase II repressing transcription factor binding	GO:0001103	IEA:EnsemblFungi
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly	GO:0051123	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29902
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.65|      14|      16|     173|     186|       1
---------------------------------------------------------------------------
  173-  186 (25.83/12.87)	PRQSKKTPVHTPAG
  190-  203 (20.82/ 8.91)	PRTAAQTPLSVPSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      30.71|      13|      16|     127|     140|       2
---------------------------------------------------------------------------
  134-  150 (17.52/ 6.80)	VPTAPVGkksaVST.PAN
  153-  168 (13.19/ 8.01)	KPSPSVG..ptASSaAAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.45|      18|      18|     225|     242|       3
---------------------------------------------------------------------------
  225-  242 (32.26/16.57)	MNSTIS.........MPQHI..LSSAMSP
  244-  263 (27.33/13.00)	MGSTMG.........TPNNMnqMSSSQQP
  280-  306 (20.86/ 8.31)	ANPAAStnntsaqslTPANI..LSMNNGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.79|      14|      16|      86|      99|       4
---------------------------------------------------------------------------
   86-   99 (24.80/17.43)	IQTLSARFHEIQ..PL
  103-  118 (17.99/10.87)	IEQFGAVDGEKQfcPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.18|      25|      51|       1|      30|       5
---------------------------------------------------------------------------
    1-   30 (33.61/41.41)	MSLKELVPNGTKLAdlEKRMVEdtmVRDGL
   55-   79 (45.57/34.44)	MSHLDSEPQGAKTN..EERFKE...VRDNL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29902 with Med3 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PLETLGNGPTVSSIPTTVPTAPVGKKSAVSTPANNDKPSPSVGPTASSAAAKKPRKPRQSKKTPVHTPAGNPTPRTAAQTPLSVPSSSGPGGDVGVSSGAAAAAAASAMNSTISMPQHILSSAMSPMMGSTMGTPNNMNQMSSSQQPQAPQQQQQQVHAPFMGANPAASTNNTSAQSLTPANILSMNNGNMNATNAERPERYGSVDLSSM
117
326










Molecular Recognition Features






MoRF SequenceStartStop




NANANA