<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29899

Description Uncharacterized protein
SequenceMFNGNERNNGLYDSRIRSSGQQSQQQQHQQGSLWQNQTHLQTQLSSKRNMASTVHGKTPMLMANNDVFAIGPYKARKDRMRVSVLEKYEIIGYIAAGTYGKVYKAKNKKEEGNASTVSNDGVAIGDGFPAGDGNDVGKDLMDIDVDGQQGNGSTDSKYGEDKDSIGGSLDSVALMDGDKIAVSAKSNVTKKSLPAYFAIKKFKTEKEGIEQLHYVGISQSACREMSLCRELDNRNLTKLVEIFLERKNIYMVYEYAEHDLLQIIHYHSHPKKRAIPPRMIRSIMWQILDGVSYLHQNWVLHRDLKPANIMVTVDGCVKIGDLGLARKFSNLLQTLYTGDKVVVTIWYRAPELLLGARHYTPAIDIWAVGCIFAELVNLQPIFKGEEAKMDSKKSVPFQANQLQKILEVLGSPTSKNWAHLHRYPEYEAFSKFPKYRENLAGWYHSTGGRDKNLLDLLYKLLAYDPISRIDASDALDHNYFTNGDYPVSDSIFEGLNYKYPARRIHTDDNDIMNLGSAYKSKNVSSQTQSSSNNTGTATLGGLGVNRRILAAAAAAAAAVSGNGIPSKSRNVEPSRKKRR
Length579
PositionKinase
OrganismKazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBRC 10181 / NCYC 3082) (Yeast) (Saccharomyces naganishii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Kazachstania.
Aromaticity0.08
Grand average of hydropathy-0.531
Instability index40.20
Isoelectric point9.18
Molecular weight64633.40
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29899
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.02|      45|     118|     255|     302|       1
---------------------------------------------------------------------------
  255-  302 (72.71/73.01)	YAEHDLLQIIHYHSHPK...KRAIP..PRMIRSIMwQILdGvSYLHQNWV.LHR
  372-  422 (64.31/47.93)	FAELVNLQPIFKGEEAKmdsKKSVPfqANQLQKIL.EVL.G.SPTSKNWAhLHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.66|      26|     482|      31|      56|       2
---------------------------------------------------------------------------
   31-   56 (47.25/30.12)	GSLWQNQ.THLQTQLSSKRNMASTVHG
  515-  541 (39.41/24.01)	GSAYKSKnVSSQTQSSSNNTGTATLGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.00|      45|      52|      78|     127|       3
---------------------------------------------------------------------------
   65-  118 (61.23/48.04)	NDVFAIGPYkarkDRMRVSV.LEKYEIIGYIAAGTYGKVYkAKNKKEEGNastvS
  119-  168 (69.78/41.51)	NDGVAIGDGfpagDGNDVGKdLMDIDVDGQQGNGSTDSKY.GEDKDSIGG....S
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29899 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ERNNGLYDSRIRSSGQQSQQQQHQQGSLWQNQTHLQTQLSSKRNMASTVHGKT
6
58










Molecular Recognition Features






MoRF SequenceStartStop




1) GIPSKSRNVEPSRKK
2) LYDSRIR
3) RRILAAAAAAAAAVS
563
11
546
577
17
560