<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29888

Description Uncharacterized protein
SequenceMAPSKYVLQPPEDLHPYIPHFSDPDRTQESDDAKVSPTAVYPDFEPWEHKPEEDRILLNFVSKGYYVSSRVNFESISARSSLHESLPKLSDQLALQFGKVLHIRDKEVNRISGSQSTSTDLKPNANKSKHSALSTNPLAGPDFTLPTRVTLTDNRKEMWLQELSSPYTSLSKMLQYIPHGLKRRQVLEQCYTKQIPLKRAIWLIKCCYSIEAQALKSKHTQAINHEGDSTTNEVKTLYKDWTDTYVYILEKLIFEMVQYYNDPNKLKIWKREVAYFLKLLGNCYTLGLLDKEVFYHWLIKFVSKIENFEFLPLSLHILMIFWDDIVGSKISLQVADPRQENTAIDTFLVSKITDILLNKYYVISNSKSMINDEKYIINDIRKNNKIKDSLQSIIGKLVCRLFQEQSLEIFLFPSTSWELYKPCLYEITSHLKDSKSDVKKKLELISYRNDTLKNNSLLTTDEIKKSTSPSTNKSEISQVFTTSTMDPEVKVISILFVDNKFTKLLDENSAEFDWVQYIDQNPLKLSQIFQLLLWSVHPSRLSHYESNQLVAKLLLLQISSLDGFPEFEIEDTIWSLVFQIAKLSKQNMARTINVTELFHLLNILNTYGMIKVPTYIRKLISSGIMYLHDSNDKFFHVKLLINLKISPLMRSQYNMILRNIMEYDPSFYENYNFDQLNNIVTTHKNNVLPGGDLSELTKLPLSCKIILGEWYLNRLCSKSTLDCIDGEQLLRNYEIFCVRLEVFHLFYKWVEFVIYHQLLDDINTMEMLMNILLRYKMVFSQFINDHILFVKTFIYVYINVLKDKDPVAYHVTSFMPFWKFFMKTFPMALTLDSDLRIELSNVYEEEKMKREKLEKNHELVNSLYQSVSHTIDNPKETTMNFTELFHTNIRVLLSLTKQHTYVERRQARCKLLLLMNSNFRDYYKFMSIFLKRNDCDNKGLIRLISEKLLTLDQVRRIQGIEKVLELIDLGDLLMCHEIYFQTHKYDYIKGNFETILKTCQEHLPQRYHLFLRILAQFGPNTNFSKLSTRAIQTMAERNGKPMADFVHDLLFYGLKSEDGDDTDDELFESESSPSDMFYLLEFTNLWVFQAITAHQVRVMTNVYGDNISGLQAALRQFIFDVIEVSKYNELCSQLFDAVEDASSIRQIIEIVEEDFFAKCLEGDERANRRDYLIIVIELVASFSKKVEGSSASSTDIPCRSLPALQAVIYGYDVLSEVELSGLELQMTVVIKVFTMHMNAIFQDIVEGLQDPMRRQSTESFLVSVSHLFERISFNLRLKLMVYELLTSLKSYCIYASTTPHERAALGPGSSSERHTFEIPNIILNVPPFQVSSFNMNKNSSETDPVSTEGNTAATSRSPLSLGITKVRSGGTRATNTTRGRWFLYNTKSAQYDCPLAVEPYHNIANDQVKQERAVNNTCFSLSLFAATFERGNPPR
Length1435
PositionKinase
OrganismKazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBRC 10181 / NCYC 3082) (Yeast) (Saccharomyces naganishii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Kazachstania.
Aromaticity0.11
Grand average of hydropathy-0.240
Instability index43.30
Isoelectric point6.28
Molecular weight166569.41
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29888
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.55|      47|     156|     597|     648|       1
---------------------------------------------------------------------------
  597-  648 (74.68/55.70)	LFH.LLNILNTYGMIkvptyIRKLISSGIMYLHDSNDKFFHVKLLINLKISPL
  754-  801 (77.87/46.78)	IYHqLLDDINTMEML.....MNILLRYKMVFSQFINDHILFVKTFIYVYINVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.92|      15|      66|     189|     208|       5
---------------------------------------------------------------------------
  189-  204 (24.75/14.88)	QCYTKQIpLKRAI...WLI
  282-  299 (22.18/ 6.32)	NCYTLGL.LDKEVfyhWLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.62|      16|     156|     958|     979|       6
---------------------------------------------------------------------------
  721-  736 (29.93/13.95)	LDCIDGEQLLRNYEIF
  964-  979 (29.68/13.72)	LELIDLGDLLMCHEIY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29888 with Med12 domain of Kingdom Fungi
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