<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29888

Description Uncharacterized protein
SequenceMAPSKYVLQPPEDLHPYIPHFSDPDRTQESDDAKVSPTAVYPDFEPWEHKPEEDRILLNFVSKGYYVSSRVNFESISARSSLHESLPKLSDQLALQFGKVLHIRDKEVNRISGSQSTSTDLKPNANKSKHSALSTNPLAGPDFTLPTRVTLTDNRKEMWLQELSSPYTSLSKMLQYIPHGLKRRQVLEQCYTKQIPLKRAIWLIKCCYSIEAQALKSKHTQAINHEGDSTTNEVKTLYKDWTDTYVYILEKLIFEMVQYYNDPNKLKIWKREVAYFLKLLGNCYTLGLLDKEVFYHWLIKFVSKIENFEFLPLSLHILMIFWDDIVGSKISLQVADPRQENTAIDTFLVSKITDILLNKYYVISNSKSMINDEKYIINDIRKNNKIKDSLQSIIGKLVCRLFQEQSLEIFLFPSTSWELYKPCLYEITSHLKDSKSDVKKKLELISYRNDTLKNNSLLTTDEIKKSTSPSTNKSEISQVFTTSTMDPEVKVISILFVDNKFTKLLDENSAEFDWVQYIDQNPLKLSQIFQLLLWSVHPSRLSHYESNQLVAKLLLLQISSLDGFPEFEIEDTIWSLVFQIAKLSKQNMARTINVTELFHLLNILNTYGMIKVPTYIRKLISSGIMYLHDSNDKFFHVKLLINLKISPLMRSQYNMILRNIMEYDPSFYENYNFDQLNNIVTTHKNNVLPGGDLSELTKLPLSCKIILGEWYLNRLCSKSTLDCIDGEQLLRNYEIFCVRLEVFHLFYKWVEFVIYHQLLDDINTMEMLMNILLRYKMVFSQFINDHILFVKTFIYVYINVLKDKDPVAYHVTSFMPFWKFFMKTFPMALTLDSDLRIELSNVYEEEKMKREKLEKNHELVNSLYQSVSHTIDNPKETTMNFTELFHTNIRVLLSLTKQHTYVERRQARCKLLLLMNSNFRDYYKFMSIFLKRNDCDNKGLIRLISEKLLTLDQVRRIQGIEKVLELIDLGDLLMCHEIYFQTHKYDYIKGNFETILKTCQEHLPQRYHLFLRILAQFGPNTNFSKLSTRAIQTMAERNGKPMADFVHDLLFYGLKSEDGDDTDDELFESESSPSDMFYLLEFTNLWVFQAITAHQVRVMTNVYGDNISGLQAALRQFIFDVIEVSKYNELCSQLFDAVEDASSIRQIIEIVEEDFFAKCLEGDERANRRDYLIIVIELVASFSKKVEGSSASSTDIPCRSLPALQAVIYGYDVLSEVELSGLELQMTVVIKVFTMHMNAIFQDIVEGLQDPMRRQSTESFLVSVSHLFERISFNLRLKLMVYELLTSLKSYCIYASTTPHERAALGPGSSSERHTFEIPNIILNVPPFQVSSFNMNKNSSETDPVSTEGNTAATSRSPLSLGITKVRSGGTRATNTTRGRWFLYNTKSAQYDCPLAVEPYHNIANDQVKQERAVNNTCFSLSLFAATFERGNPPR
Length1435
PositionKinase
OrganismKazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBRC 10181 / NCYC 3082) (Yeast) (Saccharomyces naganishii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Kazachstania.
Aromaticity0.11
Grand average of hydropathy-0.240
Instability index43.30
Isoelectric point6.28
Molecular weight166569.41
Publications
PubMed=22123960

Function

Annotated function 
ECO:0000256	RuleBase:RU364147
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi
GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi
GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi

Interaction

Binary Interactions











Repeat regions





Repeats
>MDP29888
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.55|      47|     156|     597|     648|       1
---------------------------------------------------------------------------
  597-  648 (74.68/55.70)	LFH.LLNILNTYGMIkvptyIRKLISSGIMYLHDSNDKFFHVKLLINLKISPL
  754-  801 (77.87/46.78)	IYHqLLDDINTMEML.....MNILLRYKMVFSQFINDHILFVKTFIYVYINVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.92|      15|      66|     189|     208|       5
---------------------------------------------------------------------------
  189-  204 (24.75/14.88)	QCYTKQIpLKRAI...WLI
  282-  299 (22.18/ 6.32)	NCYTLGL.LDKEVfyhWLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.62|      16|     156|     958|     979|       6
---------------------------------------------------------------------------
  721-  736 (29.93/13.95)	LDCIDGEQLLRNYEIF
  964-  979 (29.68/13.72)	LELIDLGDLLMCHEIY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29888 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) YIPHFSDPDRTQESDDAKVSPTAVYPDFEP
17
46










Molecular Recognition Features






MoRF SequenceStartStop




1) MAPSKYVLQPPEDLHPYIPHFSDPDRTQESD
2) TAVYPDFEP
1
38
31
46