<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29879
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MNVTPLDELQWKSPEWIQVFGLRTENVLDYFAESPFFDKTSNNQVIKMQRQFSQLNDPNVSVNMSQNIMNLSDGKNGNVEDEFAYVDPARKQILFKYPMYRQLEEELMKLGGTEYVLSSVREPDFWTIKKQKRVNETGAGSSRGPKIIPLQDYYIIGANVYQSPTIFKIVQSRLMSTSYHLSSTLESLYDLIEFQPSQGVHYKVPIDTSTIATAATNGNNANGGSNKNSVRPTGGANITTIPSTTNVNMTVNTVGTGGQTIDNGAGRASNGNTGITTEMLDKLMVTSIRSTPNYI |
Length | 295 |
Position | Head |
Organism | Saccharomyces kudriavzevii (strain ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889) (Yeast) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Saccharomyces.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.471 |
Instability index | 41.33 |
Isoelectric point | 5.81 |
Molecular weight | 32751.38 |
Publications | PubMed=12775844
PubMed=22384314
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 PIRNR:PIRNR013286
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coactivator activity GO:0003713 IEA:EnsemblFungi
|
GO - Biological Process | positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly GO:0051123 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP29879
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 90.14| 28| 50| 26| 57| 1
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26- 57 (39.99/40.52) NVLDYFAespFFDkTSNNQVIKMQRQFSQLND
78- 105 (50.15/34.83) NVEDEFA...YVD.PARKQILFKYPMYRQLEE
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