<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29877
Description |
Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MSLQNNVLNQIQQVLLPTSPDLNEPNGDIIKEESSSMENGDEKDHLTIQQQPSNLSAPSTNSNGEFIPHIFYSLHQIRKDPNNLSNQLETSTGSIRHRLKLCKSLISENEDAKKLLSKSPSEWQDIIHQREQELQIKRDVLDDLHRKLQR |
Length | 150 |
Position | Middle |
Organism | Saccharomyces kudriavzevii (strain ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889) (Yeast) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Saccharomyces.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.943 |
Instability index | 49.52 |
Isoelectric point | 5.65 |
Molecular weight | 17228.00 |
Publications | PubMed=12775844
PubMed=22384314
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
cytosol GO:0005829 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | structural molecule activity GO:0005198 IEA:EnsemblFungi
transcription coactivator activity GO:0003713 IEA:EnsemblFungi
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly GO:0051123 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP29877
No repeats found
|