<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29868
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MAPIDTRVNHDAIEQQLKDIIQDLYQIMVQVSTYDSMGRPSKDVLSNEMTTLSRSLQTLHTSASAPDALPSVPPELIEYVENGRNPDIYTREFVELVRRGNQLMSGKMRAFGAFRDVLARNVATAMPELRDDVVQVVEATGGTRVAVALNSTSNTTPAAPPAAADPGSGTTAAAAAAAAAAAAAAAPGAPDGAATTLG |
Length | 198 |
Position | Middle |
Organism | Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus) (Tritirachium shiotae) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Cordycipitaceae> Beauveria.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.108 |
Instability index | 41.70 |
Isoelectric point | 4.76 |
Molecular weight | 20575.85 |
Publications | PubMed=22761991
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP29868
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.03| 15| 18| 66| 83| 2
---------------------------------------------------------------------------
66- 83 (22.73/24.08) PDALPsvpPELIEYVENG
86- 100 (27.30/18.27) PDIYT...REFVELVRRG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 63.26| 20| 26| 1| 23| 3
---------------------------------------------------------------------------
1- 23 (28.96/25.72) MAPIDTrvnHDAIEQQLKDIIQD
28- 47 (34.30/21.60) MVQVST...YDSMGRPSKDVLSN
---------------------------------------------------------------------------
|