<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29857

Description Serine/threonine-protein kinase
SequenceMPLGSRPTAGHGSRQQQPQPQYPQLQQRSGTQWNSSAAAPHMSFAPSSRSGGSSFLAPTSTHRNQNYAHRRIPEGVGRSGGYQPKARVTERYRIVGFISSGTYGRVYKAVNRNNIVTSTNGATVATGHEVAIKKFKPDKEGEQISYTGISQSAIREMSLCSELNHANVIRLIEIILEDKCIFMVFDYAEHDLLQIIHHHTQQPRHPIPPATVKSIMFQLLNGCHYLHTNWVLHRDLKPANIMVTSSGGVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSYHYTPAIDMWAIGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMMKIMEIMGAPTKDKWPLLSTMPEFGQLNALQASMAAHHGRHSHGAPLASNLEKWYHNTISNAPSSTNTSSGASTSLSSLGQEGYRLLSGLLEYDPVRRLTAAQALQLPFFSTGDKVTANAFEGLKVDYPHRRVSQDDNDIRTSSLPGTKRSGLADDSLLRPSKRVRE
Length501
PositionKinase
OrganismBeauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus) (Tritirachium shiotae)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Cordycipitaceae> Beauveria.
Aromaticity0.08
Grand average of hydropathy-0.441
Instability index49.06
Isoelectric point9.66
Molecular weight55573.53
Publications
PubMed=22761991

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29857
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.39|      18|      20|      28|      45|       1
---------------------------------------------------------------------------
    6-   23 (34.00/18.04)	RPTAGHGSRQQQPQPQYP
   28-   45 (33.39/17.60)	RSGTQWNSSAAAPHMSFA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.86|      20|      20|      75|      94|       2
---------------------------------------------------------------------------
   75-   94 (36.37/23.36)	GVGRSGGYQPKARVTERYRI
   96-  115 (32.49/20.06)	GFISSGTYGRVYKAVNRNNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.26|      30|     319|     126|     159|       3
---------------------------------------------------------------------------
  126-  159 (47.25/46.17)	TGHEVAIKKFkpdkEGEQISYTG..ISQ..SAIREMSL
  446-  479 (44.01/31.46)	TGDKVTANAF....EGLKVDYPHrrVSQddNDIRTSSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.05|      21|      26|     192|     212|       4
---------------------------------------------------------------------------
  192-  212 (40.44/19.10)	LLQII...HH.HTQQPRH.PIPPATV
  216-  241 (26.61/10.78)	MFQLLngcHYlHTNWVLHrDLKPANI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29857 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DYPHRRVSQDDNDIRTSSLPGTKRSGLADDSLLRPSKRVRE
2) MPLGSRPTAGHGSRQQQPQPQYPQLQQRSGTQWNSSAAAPHMSFAPSSRSGGSSFLAPTSTHRNQNYAHRRIPEGVGRSGGYQ
461
1
501
83










Molecular Recognition Features






MoRF SequenceStartStop




NANANA