<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29854

Description Mediator of RNA polymerase II transcription subunit 31
SequenceMKGAIILAAAGLVAAQLPDISNVPQCAITCLLPALSSTGCDLTDLTCACKSENQEKIRSSATPCLEKGCSKDDLQKALDAANSLCGGGVSGIPSGSATSTGAASTGSQSASSGSASGSSPAVITSSATPTSGAGGIVPPVTSAVSSGFSTALPGNGTATTRTSTRSASGSSSATSSGSQTSSTGAPGTNDAAGPVAGVIAAIAAAVFALLIGLVFGMLSRARTVLQVAIGYHLVAEDSSDTKLQKRVFQWSISETRRRDLIQQYVKIRWRGLWGRVQRHTDRPLSAPATTSAEPLHRRIRKEILKEIPAFDSPSRIVSVGDSLDVVQASTQQYLTTNTAHTATNSRASRSQRRLPLPTPKYMAADLSDVHMASPPTLPEQNEPRWGGYSRFEIELEFVQSLANPFYLNHLASQKLLTQPAFVAYLAYLRYWSRPPYLKYLTYPGPTLRHLELLQQERFRQDIMSPDLVARLVEEGMRSAVQWHREGAA
Length488
PositionMiddle
OrganismBeauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus) (Tritirachium shiotae)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Cordycipitaceae> Beauveria.
Aromaticity0.06
Grand average of hydropathy-0.162
Instability index57.45
Isoelectric point9.24
Molecular weight51649.74
Publications
PubMed=22761991

Function

Annotated function 
GO - Cellular Component
anchored component of membrane	GO:0031225	IEA:UniProtKB-KW
cell wall	GO:0005618	IEA:UniProtKB-KW
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29854
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.43|      18|      19|     117|     134|       2
---------------------------------------------------------------------------
  115-  132 (31.66/13.77)	ASGSSPAVITSSA......TPTSG
  133-  154 (20.75/ 6.69)	AGGIVPPV..TSAvssgfsTALPG
  167-  184 (28.03/11.41)	ASGSSSATSSGSQ......TSSTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.05|      20|      27|      33|      53|       3
---------------------------------------------------------------------------
   33-   53 (33.33/25.16)	PALSStGCDLTDLTCACKSEN
   63-   82 (36.72/22.98)	PCLEK.GCSKDDLQKALDAAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.85|      10|      16|     203|     212|       4
---------------------------------------------------------------------------
  203-  212 (15.69/ 9.41)	AAAVFALLIG
  221-  230 (16.16/ 9.89)	ARTVLQVAIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      27.11|       9|      18|     287|     299|       5
---------------------------------------------------------------------------
  287-  299 ( 8.54/13.63)	PATTSaePlhRRI
  308-  316 (18.57/ 8.39)	PAFDS..P..SRI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.30|      27|      27|     384|     410|       6
---------------------------------------------------------------------------
  384-  410 (47.68/34.89)	RWGGYSRFEIELEFVQSLANPFYLNHL
  414-  440 (47.62/34.84)	KLLTQPAFVAYLAYLRYWSRPPYLKYL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29854 with Med31 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALPGNGTATTRTSTRSASGSSSATSSGSQTSSTGAPGTND
2) SATSTGAASTGSQSASSGSASGSSPAVITS
151
96
190
125










Molecular Recognition Features






MoRF SequenceStartStop




NANANA