<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29844

Description Catalase
SequenceMASTIAGAARQAYTSMTSTAKVADLQNDTVDPASQTNKGLTTDFGLYVSDTDNWLKAQDGTHTGPSLLEDQIAREKIQRFDHERIPERVVHARGTGAHGYFKVFDNRASKYTYAPVLTDPSRTTPMFVRFSTVQGSRGSADTVRDVRGFATKFYTQEGNWDIVGNNIPVFFIQDAIKFPDFVHAVKPEPHNEVPQGQTAHNNFWDFVGLQPESAHMVMWAMSDRGIPRSFRMMQGFGVNTFTLMNAKNERFFVKFHWLPELGVHSFVWDEALKVCGQDPDFHRKDLEEAIEAGAYPKWKFAIQCIPEANEHDFDFDILDSTKVWPEELVPLEVIGEMTLDKTVDEFFPETEQAAFCTSHVVPGIGFSDDPLLQGRNFSYFDTQITRLGVNWQELPINRPVCPVMNHNRDGQMRHRITKGQINYWPNRKEVAGPVPVSQGGYADFAQKVAGIKQRVRTPKFQEHFNQAQLFYNSLTPYEKAHLINAASFELSHCDDPVVFETYTKLLNNIDFNLAKQVAINVGGIVPDKPARHNHGQVTPTLSQLYYAPKEPTIVSRRIAILVADGFNLAEVEGLRAAFKAGQATTWIIGPRRGYVYPAGEVVGEGSGVWADHHYEGQRSTLFDAFIIPSGAEHAQKLAQNGRTIHWVREAFGHCKAIGALGEGIVFLREAVQLPGVQFAQNLKSDTVTTSYGVVTAGKYDSASFAADALKIGQDEKGFVSNFAYEYWIIAFWLWPITQVFPFKELPFRAKEHRLSHLVIMDLNDLHPPDDYSHRFFIWHEWIQAHGPLTNENVFDYFATSMFYDKQSNNQVLRMQTMHTGMPLENEAEELRRFTGVEFAVVHAEPPSMFIIHKRERLSPDEGTSSAARNPKMSNSSCCPNVYTLVSNRLLTSLNALQTSLQSLRTHRPSYTPRTGFVWPIIEPPAPDDASKQRGTSEGPASSTDDQDLSGPPAKRKPPAVHERQQNNMLLYNAMHTTAVHASASFTLPVAAAESTAPDTPVSGPGPRFSATPAPAPTRGATPKVAAAPQEPIPAKGPPGGGKKKKKRTATMSSAG
Length1055
PositionHead
OrganismFibroporia radiculosa
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Polyporales incertae sedis> Fibroporia.
Aromaticity0.10
Grand average of hydropathy-0.418
Instability index35.21
Isoelectric point6.41
Molecular weight117578.04
Publications
PubMed=22247176

Function

Annotated function Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. 
ECO:0000256	ARBA:ARBA00003918
ECO:0000256	RuleBase:RU004142
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
catalase activity	GO:0004096	IEA:UniProtKB-EC
heme binding	GO:0020037	IEA:InterPro
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
hydrogen peroxide catabolic process	GO:0042744	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
response to oxidative stress	GO:0006979	IEA:InterPro

Interaction

Binary Interactions











Repeat regions





Repeats

>MDP29844
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     279.32|      72|      78|     821|     898|       1
---------------------------------------------------------------------------
  803-  872 (108.50/59.19)	...YDKQSNNQVLRMQTMHTgM.PLENEAEELRRFTGVEFAV..VHAEPPSMFIIHKRERLSPDEGTSS.........AARNPKM
  879-  957 (91.71/58.64)	PNVYTLVSNRLLTSLNALQTsLqSLRTHRPSYTPRTGFVWPI..IE..PPAPDDASKQRGTSEGPASSTddqdlsgppAKRKP..
  958- 1008 (79.10/38.18)	PAVHERQQNNMLL.YNAMHT......................taVHASASFTLPVAAAESTAPDTPVSG.........PG..PRF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     249.73|      81|     321|      29|     120|       4
---------------------------------------------------------------------------
   29-  120 (126.29/111.49)	TVD...PASQTNKGLTTDF..GLYVSDtDNWLKAQDgthtgPSLLEDQIAREKI..QRFDHER.IPERVVHAR.GTGAH....GYFKVFDNRasKYTYAPVltdP
  342-  435 (123.45/80.26)	TVDeffPETEQAAFCTSHVvpGIGFSD.DPLLQGRN.....FSYFDTQITRLGVnwQELPINRpVCPVMNHNRdGQMRHritkGQINYWPNR..KEVAGPV...P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.12|      13|     521|     250|     262|       6
---------------------------------------------------------------------------
  250-  262 (26.10/15.51)	RFFVKFHWLPELG
  774-  786 (28.02/17.22)	RFFIWHEWIQAHG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29844 with Med6 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASASFTLPVAAAESTAPDTPVSGPGPRFSATPAPAPTRGATPKVAAAPQEPIPAKGPPGGGKKKKKRTATMSSAG
2) PRTGFVWPIIEPPAPDDASKQRGTSEGPASSTDDQDLSGPPAKRKPPAVHERQQNNMLLYNAMH
981
912
1055
975










Molecular Recognition Features






MoRF SequenceStartStop




1) APTRGATPKVAAAPQEPIPAKGPPGGGKKKKKRTATMSSAG
1015
1055