<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29843

Description Uncharacterized protein
SequenceMLEEGPMATLMNDPMRLYRARRDAERKRVTEKYLIEGFISSGTYGRVYKAKSRDSDGRIHAIKKFKPDKEGDIITYTGISQSAIREIALNREISHENVVALKEVILEDKSIYMVFEYAEHDFLQVIHHHSQTLRTGITLPVLKSLTYQLLNGLLYLHTVHIIHRDLKPANILITASGVVKIGDLGLARLTHQPLQPLFAGDKVVVTIWYRAPELLLGAKHYNKAVDVWAVGCVMAELASLRPIFKGEEAKLDSKKNVPFQKDQLLKIFEVLGTPDEREWPGVKTLPEYQNMKRLDVYKNHLLDWFQSRTRSTEGYELLRLLFAYDPDNRLTAKEALQNKWFHEDPKPTANAFQSLPPHQIPPQRRISHDDAPSMIPLPAASQSQAQSQVQAQIAQVQAQAQAHLSAQLSHSHSGKPGSAASFASLSGGATGIGSGHARKKARIG
Length444
PositionKinase
OrganismFibroporia radiculosa
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Polyporales incertae sedis> Fibroporia.
Aromaticity0.07
Grand average of hydropathy-0.376
Instability index37.54
Isoelectric point9.34
Molecular weight49833.55
Publications
PubMed=22247176

Function

Annotated function 
GO - Cellular Component
euchromatin	GO:0000791	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:EnsemblFungi

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29843
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.14|      16|      16|     322|     337|       1
---------------------------------------------------------------------------
  322-  337 (27.87/19.76)	FAYDPDNRLTAKEALQ
  341-  353 (24.83/16.78)	FHEDPKP..TA.NAFQ
  358-  371 (19.44/11.50)	HQIPPQRRISHDDA..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.16|      15|      34|     255|     269|       2
---------------------------------------------------------------------------
  255-  269 (25.74/14.41)	KNVPFQKDQLLKIFE
  292-  306 (27.41/15.73)	KRLDVYKNHLLDWFQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.09|      10|      29|      16|      25|       3
---------------------------------------------------------------------------
   16-   25 (18.25/13.36)	RLYRAR.RDAE
   46-   56 (13.83/ 8.40)	RVYKAKsRDSD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29843 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EALQNKWFHEDPKPTANAFQSLPPHQIPPQRRISHDDAPSMIPLPAASQSQAQSQVQAQIAQVQAQAQAHLSAQLSHSHSGKPGSAASFASLSGGATGIGSGHARKKARIG
334
444










Molecular Recognition Features






MoRF SequenceStartStop




1) HARKKARIG
436
444