<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29835

Description Uncharacterized protein
SequenceMFSQWRQAVENLAQHPPRQDSADERQSRSSLDTGLRASLSSAQLAESALSNIKKTLAAQRSGSPSPSLSHASHSPGADIGPKRPASQSTTRTTLEDRLRAKFAISDNSSSPTPVSSSGSSPSLRVVIDHPLSPTSAPLPESPAPQRVGSADPFDALSKVRHFSPTASVDDTTSNVSASLPAARGPTFQTPPSPALIPLPDSPALAPTAESPVPLDSLESQCNSGGDSAISVDQGGTDVVVLDEITGDATKSVINYASLQDHVVGVVDDTHGATVFQQDQHVKDSGYAPTTIALPSSVEEHDGPGDLSPGRSTIEADAKEYVPDAPLDTITTAQGAKHIRDAQPIPSNQTSPHDWTGRTIPEDVASKSSEPNVEELQRRLKLVEQRFAVPSGDDTDVSTSFKRLQAEKIAADKVVKELTPLETLKDVDALRDYLQNVNIKTEMAQDEIRRLSGKLTRQEERIDELREIHRLESKSQSDQIEKLKGQVSESEALLKASQSSNVQVEEEVLKWKAETERLQSEMERLKGLSKEEEEKRVKAVALLKTVRQKLVKAEKERDDAIKDTQQIKEKDKEELEKDKAEKLELRQEIERANTEHETALVGLKLHFEKESVMLKDRQEKELLAVRGQYELEALAVKSSYTRELEVKDSRIRELQNSVRVLNEEKDEFFDQLQLRQAELESSRSRLEVLEGQTTEFQYQLREANDRIALLSEELADARREQDIRPQNAGPSAEEVTRLLSAAEAKYETRMADMRRRLSAVEKERDEGEAQWSRKLSEKVKELESLRGSLHSSTRSREEESESANALRKEIQGLKGEILAYQQRVSDLQVQADTVAEAENATKSEIAENNARMLALQQTIEESKNREAQVRAHNKTLREELRKVQSSAALLERQRNPGVGYWASRQENTADARSPRSSISESSPQDHPSRPGSPATPKSDEDLNVEYLRNVILQFLEHKEMRYEISNWNILDSVLVLFRNYPGDPGLQGYLKRAVEDQLLTLSRLVSTFLSAARSPELHNPATLDMLCRIALDSYYASGLPAMGSIVPYTQSNMELLGTVQDSMALLRTAHTLPLSQFNQLFASASELLSLLLSCVADISQISTTQAMMYFAEASDVLQVLRLPLGVRQQLENFALSLSLLLGDDAKAMREAQMMHTLQLAWFCTASAGEFGAGASDHAVAVLVGLFRWTSWTPVVFYTQLLHSALTCIAQTLASLASSRTSLIWRALIVGRLPHLFSRFQKEAETESGTDADWRTALQAALSSVLRRSDILSKYETSSNSHETDLGKPRTSSNLAIELLHEFVTVGLVDASFATTLCPTLQNDFHSPLTVEAQDAGSDVRSYLESKFAFDANLDDIVSAVDRICRDPCSHSVFADIVLKRCTPSPRPLELDSLSQMSRVLTRCEPALDIIALHVNIPNLITHVLAFVEDYDCETVGDPQTAVSHLGDVVLFVQEAVARFNFSYPTVTLGDRKLDLAVIRPTAVVYPVSQLGHDSNVFYLWFKALFDTNSEGIEDTILRTTRPQALLRIAATLFSHAIAMTTERKMDKEILQNGILYFLGPLLNWTLSGVVNFLIMEIQHRGFNAPVHIDVLQTLLSSSSCPPTVLRLSASKILRLFPNSPKNESGRMNSLDFTAIRHVAMKGLGVPVEGKSDPPLSLHAQPPGWSDLSLRSVRDALTAARSGKAPALDIDRCLLLTPPAKFLHMLWKELMVMASLGEIDISRRIATFVLTMPRRSHSPPLLPIFLHVLLPGLVAAADSLPSSDPTVTVELLVTVVSSSLTAALHLEYALLKTDKEHSPVLGQTTAAMARRLGSDLRRKGHGRTAALIVQRLCSISTFMTNFPTFMADV
Length1847
PositionTail
OrganismFibroporia radiculosa
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Polyporales incertae sedis> Fibroporia.
Aromaticity0.05
Grand average of hydropathy-0.345
Instability index54.98
Isoelectric point5.49
Molecular weight203908.87
Publications
PubMed=22247176

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29835
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.50|      32|      32|    1008|    1039|       1
---------------------------------------------------------------------------
  127-  144 (24.58/ 8.54)	.................IDHPLSPTSAPLPESPAP
  179-  213 (54.52/28.55)	LPAARGPTFQtppSPALIPLPDSPALAPTAESPVP
 1008- 1039 (55.40/29.13)	LSAARSPELH...NPATLDMLCRIALDSYYASGLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     142.44|      32|      82|    1054|    1085|       2
---------------------------------------------------------------------------
 1062- 1093 (51.91/27.95)	MALLRTAHTLPLSQFNQLFA.SASELLSLLLSC
 1094- 1114 (23.51/ 8.86)	VADISQIST...TQAMMYFA.EASD........
 1116- 1146 (37.33/18.16)	LQVLRL..PLGVRQQLENFAlSLSLLLGDDAKA
 1147- 1168 (29.69/13.02)	MREAQMMHTLQLAWFCT..A.SAGE........
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     504.09|      82|      82|     485|     566|       3
---------------------------------------------------------------------------
  364-  434 (54.26/26.47)	...........ASKSSEPNVEELQRRLKLVEQRFavpsgddtdvSTSFKRLQA..EKIA..AD.KVVKE.....LTPLETLKD..V..............DA.LRDYLQ......
  438-  486 (31.71/12.30)	............................IKTEMA..........QDEIRRLSGkLTRQE..ERiDELRE.....IHRLES......KS.......QSDQIEK.LKG..Q.....V
  488-  566 (110.95/62.09)	...ESEAL.LKASQSSNVQVEEEVLKWKAETERL..........QSEMERLKG.LSKEE..EE.KRVKA.....VALLKTVRQKLVKA.......EKERDDA.IKDTQQ.....I
  567-  624 (54.81/26.81)	..........KEKD......KEELEKDKAEKLEL..........RQEIER.....ANTE..HE.T...A.....LVGLK...LHF..........EKE.SVM.LKDRQEkellaV
  627-  690 (65.65/33.63)	QY.ELEALaVKSSYTRELEVKDSRIR......EL..........QNSV.RVLN.EEKDEffDQ..............LQ.LRQ....A.......ELESSRS.RLEVLE.....G
  691-  774 (81.65/43.68)	QTTEFQYQ.LREANDRIALLSEEL....ADARRE..........QDIRPQNAG.PSAEE..VT.RLLSAaeakyETRMADMRRRLSAV.......EKERDEGeAQWSRK.....L
  777-  831 (56.75/28.03)	KVKELESL.RGSLHSSTRSREEE....SESANAL..........RKEIQGLKG..............EI.....LAYQQRVSDLQVQA.......D...................
  833-  897 (48.31/22.73)	.VAEAE....NATKS..............EIAEN..........NARMLALQQ.TIEES..KN.REAQV.....RAHNKTLREELRKVqssaallERQRNPG.V...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     308.77|      81|      83|    1572|    1652|       4
---------------------------------------------------------------------------
 1521- 1566 (54.69/32.66)	............................PQALLRIAAT....LFSHAI.....AMTTER..KMDKEIL.QNGILYFLG.PLLNWTLS
 1572- 1652 (134.88/93.70)	LIMEIQHRGFNAPVHIDVLQTLLSSSSCPPTVLRLSASKILRLFPNSP.....KNESGRMNSLDFTAI.RHVAMKGLGVPVEGKSDP
 1654- 1738 (119.20/81.76)	LSLHAQPPGWSDLSLRSVRDALTAARSGKAPALDID..RCLLLTPPAKflhmlWKELMVMASLGEIDIsRRIATFVLTMPRRSHSPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.21|      50|      54|      15|      68|       5
---------------------------------------------------------------------------
   15-   68 (71.78/52.14)	HPPRQDSADER.QSRSSLDTGLRASLsSAQLAESalSNIKKTLAAQRSGSpSPSL
   73-  123 (83.44/46.15)	HSPGADIGPKRpASQSTTRTTLEDRL.RAKFAIS..DNSSSPTPVSSSGS.SPSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     128.52|      37|      83|     216|     252|       6
---------------------------------------------------------------------------
  216-  239 (32.09/16.06)	.....................SLESQCNSG....GDSAISV..DQGGTDVV
  240-  275 (37.09/19.79)	VLDE...I.TGDATKSVinyaSLQ...........DHVVGVvdDTHGATVF
  276-  321 (38.73/21.00)	QQDQhvkD.SGYAPTTIalpsSVEEHDGPGdlspGRSTIEA..D..AKEYV
  325-  353 (20.61/ 7.51)	PLDT...ItTAQGAKHIrdaqPIPSNQTSP....HD...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.93|      15|      28|    1223|    1237|       7
---------------------------------------------------------------------------
 1223- 1237 (27.31/19.41)	WRALIVGRLPHLFSR
 1252- 1266 (24.62/16.61)	WRTALQAALSSVLRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     227.94|      75|     826|     929|    1007|       8
---------------------------------------------------------------------------
  929- 1007 (124.85/99.69)	PG....SPATPKSDEDLNVEYLRNVILQ......FLEHKEMRYEISNWNIL.DSVLVLFRNYPGDPGLQGYLKRAVedqlLTLSRL..VSTF
 1749- 1836 (103.08/72.56)	PGlvaaADSLPSSDPTVTVELLVTVVSSsltaalHLEYALLKTDKEHSPVLgQTTAAMARRLGSDLRRKGHGRTAA....LIVQRLcsISTF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29835 with Med5 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ESALSNIKKTLAAQRSGSPSPSLSHASHSPGADIGPKRPASQSTTRTTLEDRLRAKFAISDNSSSPTPVSSSGSSPSLRVVIDHPLSPTSAPLPESPAPQRVGSADPFDALSKVRHFSPTASVDDTTSNVSASLPAARGPTFQTPPSPALIPLPDSPALAPTAESPVPLDSLESQCNSGGDSAISVDQGGTDVVVLDE
2) PGVGYWASRQENTADARSPRSSISESSPQDHPSRPGSPATPKSDE
3) QVQADTVAEAENATKSEIAENNARMLALQQTIEESKNREAQVRAHNKTLRE
4) QWRQAVENLAQHPPRQDSADERQSRSSLDTGLRASLSSAQL
5) VDDTHGATVFQQDQHVKDSGYAPTTIALPSSVEEHDGPGDLSPGRSTIEADAKEYVPDAPLDTITTAQGAKHIRDAQPIPSNQTSPHDWTGRTIPEDVASKSSEPNVEELQRRLKLVEQ
46
895
827
4
266
243
939
877
44
384










Molecular Recognition Features






MoRF SequenceStartStop




1) LSNIKKTLA
49
57