<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29718

Description "Pb, isoform D"
SequenceMQEVCSTLDTTPMGTQIKSESPLNPLQVQTGGQTALPVGVGVGGLVGQGTQQGAPAVPAVMLVNKMASNCDKRAADTAYWMAASEGGFINSQPSMAEFLNHLSPESPKMGTPVGGGGGGGVGVGGGVNVNVNVGVGYPVGVGPMPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSIKNGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGSLTPNSSLETGISSNLLGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDENQVIKKEAVSTSSKASPFGYESSTPSLVSFRRDSDAVIASANPPPTKGKKRYQNNANSIATPTPLTDSSSGGNVGAGGGGGASAGGYFPGYYPSPKQQMQQQQQLHPQQQQQQPQPQDYYGKYDIEFAASPHHNNPHKQQSLHAGEYLSPKPNAATFHQNSQQQQQHEQQFYYNYNDANGSAYMNHQQQQQQQHHHVGDFETPPINGPSNFNSGYYDNMSFQHQAQAQAHQQHQSVVFQQQQQHQQAPINHQQHMHHLGTGEAYSALGLQMENCDGYNNFGGPGSAGAGSAGAGVGVGYYEAGQQPPVPPHTHTHTHHPHHHVQVQAQAHDHLHAHHNPAAAAVQAGVGVGVGVGVGVGVVPPPPPPSHIHGFALNGGGQAVQSQAFVSGGGSAGGAAAISGLENSNSSSDFNFLSNLANDFAPEYYQLS
Length796
PositionKinase
OrganismDrosophila pseudoobscura pseudoobscura (Fruit fly)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.784
Instability index54.71
Isoelectric point6.20
Molecular weight84582.17
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29718
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     441.41|      78|      79|     472|     549|       1
---------------------------------------------------------------------------
  352-  407 (53.83/14.88)	..................DIE.ESSPIKVKKKDENQ....VIKKE.............A..VSTSSKA.SPFGYESS....TPSL..VSFRRDSDA.....VIASA.
  409-  475 (51.27/13.85)	........PPPTKGKKRYQNN.ANSIATPTPLTDSSsggnVGAGGgggasaggyfpgyY..PSPKQ.......QMQQ....QQQLHPQQ..................
  476-  549 (134.23/46.93)	....QQQQPQPQDYYGKYDIEFAASPHHNNPHKQQS....LHAGE.............Y..LSPKPNA.ATFHQNSQ....QQQQHEQQFYYNYND.....ANGSAY
  552-  630 (97.67/32.36)	HQQQQQQQ...HHHVG..DFE...TPPINGPSNFNS.......GY.............YdnMSFQHQAqAQAHQQHQsvvfQQQQQHQQAPINHQQhmhhlGTGEAY
  665-  706 (59.75/17.24)	YYEAGQQPPVPPHTH.....THTHHPHH...HVQVQ....AQAHD.............H..LHAHHNP.A.....................................
  730-  764 (44.66/11.22)	.......PPPPSHIH.......................................................GFALNGG....GQAVQSQAFVSGGGS.....AGGAA.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     173.53|      51|      80|       8|      81|       2
---------------------------------------------------------------------------
    8-   58 (94.19/34.14)	LDTTP.MGT...QIKSESPLNPLQVQTGGQTALPVG........VGVGGLVGQG....TQQGAPAVP
   89-  155 (79.34/52.48)	INSQPsMAEflnHLSPESPKMGTPVGGGGGGGVGVGggvnvnvnVGVGYPVGVGpmpqTPDGMDSVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.56|      13|      56|     652|     664|       3
---------------------------------------------------------------------------
  652-  664 (25.68/13.03)	AGAGSAGAGVGVG
  707-  719 (24.88/12.39)	AAAVQAGVGVGVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.72|      22|      76|     159|     181|       4
---------------------------------------------------------------------------
  159-  180 (39.29/25.90)	WMKEKKTSRKSSNNNNQGDNSI
  290-  311 (34.42/16.66)	NSRGHNNNTPSATNNNPSAGSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.21|      15|      15|     251|     265|       5
---------------------------------------------------------------------------
  251-  265 (26.67/16.48)	EDNKDSLKG....DDDQSD
  268-  286 (22.53/12.74)	SNSKKSCQGcelpSDDIPD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29718 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AGAGVGVGYYEAGQQPPVPPHTHTHTHHPHHHVQVQAQAHDHLHAHHNPAAA
2) MQEVCSTLDTTPMGTQIKSESPLNPLQVQTGG
3) PVGVGPMPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSIKNGLPRRLRTAYTNT
4) SFRRDSDAVIASANPPPTKGKKRYQNNANSIATPTPLTDSSSGGNVGAGGGGGASAGGYFPGYYPSPKQQMQQQQQLHPQQQQQQPQPQDYYGKYDIEFAASPHHNNPHKQQSLHAGEYLSPKPNAATFHQNSQQQQQHEQQFYYNYNDANGSAYMNHQQQQQQQHHHVGDFETPPINGPSNFNSGYYDNMSFQHQAQAQAHQQHQSVVFQQQQQHQQAPINHQQHMHHLGTGEAYS
5) VKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGSLTPNSSLETGISSNLLGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDENQVIKKEAVSTSSKASPFGYESSTPSL
657
1
138
395
229
708
32
195
631
393










Molecular Recognition Features






MoRF SequenceStartStop




1) APEYYQLS
2) FYYNY
3) QPQDYYGKYDIEFA
4) SAGGYFPGYYPSP
5) TKGKKRYQN
789
537
481
449
412
796
541
494
461
420