<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29694

Description Uncharacterized protein
SequenceMSACREIALLRELKHANVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPLGMVKSLLYQILDGIHYLHANWESHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVSFWYRAPELLLGARHYTKAIDNDWEDIKKMPEHSTFMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMGPIKRITSEQAMQDPYFLEDPLPTSDVFVGCQIPYPKREFLTEEEPDDKGVKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMG
Length337
PositionKinase
OrganismIctidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Sciuromorpha> Sciuridae> Xerinae> Marmotini> Ictidomys.
Aromaticity0.08
Grand average of hydropathy-0.607
Instability index46.19
Isoelectric point9.11
Molecular weight38380.52
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP29694
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.33|      28|      57|     171|     224|       1
---------------------------------------------------------------------------
  171-  199 (47.52/76.98)	FMKD..FRRNTYTNCSlIKYMEKH...KVKPDSK
  227-  259 (41.81/16.13)	FLEDplPTSDVFVGCQ.IPYPKREfltEEEPDDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.30|      15|      36|      91|     105|       2
---------------------------------------------------------------------------
   91-  105 (26.75/19.52)	DLKPANILVMGEGPE
  129-  143 (28.55/21.31)	DLDPVVVSFWYRAPE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP29694 with CDK8 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) REFLTEEEPDDKGVKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMG
248
337

Molecular Recognition Features

MoRF SequenceStartStop
1) TSGGLIMTSDY
303
313