<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29689

Description POU domain protein
SequenceMMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAGGGGGLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY
Length294
PositionHead
OrganismIctidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Sciuromorpha> Sciuridae> Xerinae> Marmotini> Ictidomys.
Aromaticity0.05
Grand average of hydropathy-0.413
Instability index53.28
Isoelectric point9.57
Molecular weight32123.44
Publications









Function






Annotated function


GO - Cellular Component
chromatin	GO:0000785	IEA:Ensembl
cytoplasm	GO:0005737	IEA:Ensembl
neuron projection	GO:0043005	IEA:Ensembl
RNA polymerase II transcription regulator complex	GO:0090575	IEA:Ensembl

GO - Biological Function
chromatin binding	GO:0003682	IEA:Ensembl
DNA-binding transcription activator activity, RNA polymerase II-specific	GO:0001228	IEA:Ensembl
GTPase binding	GO:0051020	IEA:Ensembl
RNA polymerase II cis-regulatory region sequence-specific DNA binding	GO:0000978	IEA:Ensembl
single-stranded DNA binding	GO:0003697	IEA:Ensembl

GO - Biological Process
cell migration in hindbrain	GO:0021535	IEA:Ensembl
cellular response to cytokine stimulus	GO:0071345	IEA:Ensembl
cellular response to estradiol stimulus	GO:0071392	IEA:Ensembl
central nervous system neuron differentiation	GO:0021953	IEA:Ensembl
habenula development	GO:0021986	IEA:Ensembl
innervation	GO:0060384	IEA:Ensembl
intrinsic apoptotic signaling pathway by p53 class mediator	GO:0072332	IEA:Ensembl
mesoderm development	GO:0007498	IEA:Ensembl
negative regulation of gene expression	GO:0010629	IEA:Ensembl
negative regulation of neuron apoptotic process	GO:0043524	IEA:Ensembl
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:Ensembl
negative regulation of transcription elongation by RNA polymerase I	GO:2001208	IEA:Ensembl
neuron fate specification	GO:0048665	IEA:Ensembl
neuron projection development	GO:0031175	IEA:Ensembl
peripheral nervous system neuron development	GO:0048935	IEA:Ensembl
positive regulation of apoptotic process	GO:0043065	IEA:Ensembl
positive regulation of cell cycle arrest	GO:0071158	IEA:Ensembl
positive regulation of gene expression	GO:0010628	IEA:Ensembl
positive regulation of osteoclast differentiation	GO:0045672	IEA:Ensembl
positive regulation of transcription regulatory region DNA binding	GO:2000679	IEA:Ensembl
proprioception involved in equilibrioception	GO:0051355	IEA:Ensembl
regulation of DNA-binding transcription factor activity	GO:0051090	IEA:Ensembl
regulation of neurogenesis	GO:0050767	IEA:Ensembl
sensory system development	GO:0048880	IEA:Ensembl
suckling behavior	GO:0001967	IEA:Ensembl
trigeminal nerve development	GO:0021559	IEA:Ensembl
ventricular compact myocardium morphogenesis	GO:0003223	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29689
No repeats found




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29689 with Med30 domain of Kingdom Metazoa
Unable to open file!