<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29689

Description POU domain protein
SequenceMMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAGGGGGLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY
Length294
PositionHead
OrganismIctidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Sciuromorpha> Sciuridae> Xerinae> Marmotini> Ictidomys.
Aromaticity0.05
Grand average of hydropathy-0.413
Instability index53.28
Isoelectric point9.57
Molecular weight32123.44
Publications









Function






Annotated function


GO - Cellular Component
chromatin	GO:0000785	IEA:Ensembl
cytoplasm	GO:0005737	IEA:Ensembl
neuron projection	GO:0043005	IEA:Ensembl
RNA polymerase II transcription regulator complex	GO:0090575	IEA:Ensembl

GO - Biological Function
chromatin binding	GO:0003682	IEA:Ensembl
DNA-binding transcription activator activity, RNA polymerase II-specific	GO:0001228	IEA:Ensembl
GTPase binding	GO:0051020	IEA:Ensembl
RNA polymerase II cis-regulatory region sequence-specific DNA binding	GO:0000978	IEA:Ensembl
single-stranded DNA binding	GO:0003697	IEA:Ensembl

GO - Biological Process
cell migration in hindbrain	GO:0021535	IEA:Ensembl
cellular response to cytokine stimulus	GO:0071345	IEA:Ensembl
cellular response to estradiol stimulus	GO:0071392	IEA:Ensembl
central nervous system neuron differentiation	GO:0021953	IEA:Ensembl
habenula development	GO:0021986	IEA:Ensembl
innervation	GO:0060384	IEA:Ensembl
intrinsic apoptotic signaling pathway by p53 class mediator	GO:0072332	IEA:Ensembl
mesoderm development	GO:0007498	IEA:Ensembl
negative regulation of gene expression	GO:0010629	IEA:Ensembl
negative regulation of neuron apoptotic process	GO:0043524	IEA:Ensembl
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:Ensembl
negative regulation of transcription elongation by RNA polymerase I	GO:2001208	IEA:Ensembl
neuron fate specification	GO:0048665	IEA:Ensembl
neuron projection development	GO:0031175	IEA:Ensembl
peripheral nervous system neuron development	GO:0048935	IEA:Ensembl
positive regulation of apoptotic process	GO:0043065	IEA:Ensembl
positive regulation of cell cycle arrest	GO:0071158	IEA:Ensembl
positive regulation of gene expression	GO:0010628	IEA:Ensembl
positive regulation of osteoclast differentiation	GO:0045672	IEA:Ensembl
positive regulation of transcription regulatory region DNA binding	GO:2000679	IEA:Ensembl
proprioception involved in equilibrioception	GO:0051355	IEA:Ensembl
regulation of DNA-binding transcription factor activity	GO:0051090	IEA:Ensembl
regulation of neurogenesis	GO:0050767	IEA:Ensembl
sensory system development	GO:0048880	IEA:Ensembl
suckling behavior	GO:0001967	IEA:Ensembl
trigeminal nerve development	GO:0021559	IEA:Ensembl
ventricular compact myocardium morphogenesis	GO:0003223	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29689
No repeats found




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29689 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA