<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29679

Description Mediator complex subunit 23
SequenceMVQMETQLQSIFEEVVRQIIDFCSYRMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRYYIILKPLNVLANTWILLSLYLFFFYQGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQVLYYHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSTLQIPIPHSLKFHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTSCLASASITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSIQGSPPLFLCLLWKMLLDTDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELYPVSKSLETLLDHLGGLYKFHGELFQILILSNTYMSKMRSPIPVFLLASFILCRQNYCLSVFIHIKCFCNFTFVFFSSTCSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSLRMSLYKDIMQISVSYFLVFHIKKVYIVDSIFSLPFVHQMKMCLNRSLHILIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSMKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQAINSGSPAPQSNQVPASLPVTQ
Length1217
PositionTail
OrganismIctidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Sciuromorpha> Sciuridae> Xerinae> Marmotini> Ictidomys.
Aromaticity0.11
Grand average of hydropathy0.109
Instability index46.10
Isoelectric point8.24
Molecular weight139714.85
Publications









Function






Annotated function


ECO:0000256	RuleBase:RU364146

GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29679
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      30|     307|     316|       1
---------------------------------------------------------------------------
  307-  316 (18.69/10.13)	IFFVLFQFAS
  340-  349 (19.45/10.86)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     278.80|      92|     107|     931|    1035|       4
---------------------------------------------------------------------------
  918- 1027 (134.78/105.05)	PYLPiyFGNVclrFLPVFDIVIHRFLELYPVsksleTLLDHL........GGLYKfhgELFQIlilSNTY.....MSKMRSPIPVFLLaSFIlCRQNYCLSVFIHIKCFCNFTFVFFS.STCSQ
 1028- 1135 (144.02/81.25)	PLVP..RENI.taWMNAIGLIITALPEPYWI.....VLHDRIvsvisslrMSLYK...DIMQI...SVSYflvfhIKKVYIVDSIFSL.PFV.HQMKMCLNRSLHILIGVAFYDMLLNvDQCST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.45|      15|      17|     221|     237|       5
---------------------------------------------------------------------------
  207-  226 (23.67/13.69)	LDP..ATLRFPlkgllPYDKDL
  227-  246 (19.78/17.74)	FEPqtALLRYV..leqPYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.72|      21|     750|      84|     104|       6
---------------------------------------------------------------------------
   84-  104 (40.96/29.46)	CLAMAVETGLLPPR.YYII....LKP
  836-  861 (30.76/20.20)	CLAMRSHEGNEAQVcYFIIqlllLKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.67|      13|      20|     862|     874|      11
---------------------------------------------------------------------------
  862-  874 (22.12/14.11)	NDFRNRVSDFVKE
  883-  895 (26.55/18.51)	NDWHTKHMNYHKK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29679 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA