<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29676

Description Mediator complex subunit 25
SequenceMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPELGSLIKLFSYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGYTTESLVQQIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPTDVSQDPRHMVLVRGLVLPVGGGSAPGPLQPKQPVPLPPAAPSGATLSAAPQQSLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLPPGPPGAPKPPPASQPSLVSTVAPGPGLAPPAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGHPLQLRPPQPQPQGTVGASGATGQPQPQGTTQAPPGAPQGPPGAAPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPPLLHPPPTQSWPTQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI
Length716
PositionUnknown
OrganismIctidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Sciuromorpha> Sciuridae> Xerinae> Marmotini> Ictidomys.
Aromaticity0.05
Grand average of hydropathy-0.222
Instability index58.36
Isoelectric point9.12
Molecular weight75167.71
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29676
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     383.77|      65|      65|     198|     262|       3
---------------------------------------------------------------------------
  198-  252 (91.77/20.59)	........................................PLQPPTDVSQ...DPRHMVLVRGLVLPVGGGSAPGPLQPKQP.................VPLPPAA......PSGA.T..................LSAA
  253-  315 (64.34/12.23)	PQQSL................P.PVPPqyqvpgnlsaaqvAAQNAVEAAK...NQKA...........GLGPRFSPINPLQQ.....................AAS......GVGP.P..................FSQA
  344-  412 (67.62/13.23)	PG...................P.GLAP.............PAQPGA........PS...M.AGTVAP.GGVSGPSPAQLGAPalggqqsvsnkllawsgVLEWQEK......PKPA.S..................VDAN
  446-  497 (49.63/ 7.75)	PQQLL...............................ttlgPLFRNSRMVQfhfTNKDLESLKGLYRIMGNGFA.G......C.................VHFPHTA......P...........................
  576-  668 (59.75/10.83)	PQGTTqappgapqgppgaapgP.PPPG.............PILRPQNPGA...NPQ....LRSLLL......NPPP..PQTG.................VP.PPQAslhhlqPPGApAllppphqslgqpqlgpplLHPP
  669-  705 (50.64/ 8.06)	PTQSW................PtQLPP...........raPL............PGQMLLS.......GG........PRGP.................VPQPGLQ......PS..........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.05|      18|     224|     319|     337|       4
---------------------------------------------------------------------------
  319-  337 (33.81/11.97)	PLPPGPPgAPKPPPASQPS
  551-  568 (35.24/ 9.38)	PLQLRPP.QPQPQGTVGAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.13|      20|      36|     125|     147|       5
---------------------------------------------------------------------------
  125-  147 (29.46/26.47)	EQIGQtHRVCLLICNspPYLLPA
  163-  182 (34.68/18.75)	QQIGE.RGIHFSIVS..PRKLPA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29676 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGSAPGPLQPKQPVPLPPAAPSGATLSAAPQQSLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLPPGPPGAPKPPPASQPSLVSTVAPGPGLAPPAQPGAPSMAGTVAPGGVSGPSPAQLGAPALG
2) TNHKQVQQQKLEQQRGHPLQLRPPQPQPQGTVGASGATGQPQPQGTTQAPPGAPQGPPGAAPGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPPLLHPPPTQSWPTQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMD
224
534
382
714










Molecular Recognition Features






MoRF SequenceStartStop




NANANA