<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29630

Description Uncharacterized protein
SequenceMTTVSATPQQMRERLLQAIDSQSNICNMVVVLEVIACLEKYPITKEALEETRLGKLINDVRKKTKDEDLAKRAKKLLRNWQKLIEPGPPVAASVPGSTNGSSHPCRTDASPSDISVPGKGVPEVKIRNDVHNTYSPKAEKSSSRKRRAEHRDSGVYLQEKISKMSPYDNSVSTPPTNGIAGSPDALPDQEVVPSPDRSRVEHLDNDKMNRIPVNAVKPRPSSPGVAKLPSTSSLIKVAVMQQQARLDEGGGGYYQARSPRGLTTSPRSTKQDTMTKRSSAYAPKGTPVPSPSSRDSPLSFSHTVSSPASSYADKLPHSSNRSSMHWASSSEASSLCPSQDISATLESPSVSPSPSLSQQNSEPHRQMSEGAMVVSDDADGTTVPNSEHKRRKYRSRDYSVNLDGQKMEDTTKPVRLKERRLTFDPVTGQIKPLVHKEPSQTDEAPTPDPPESRQRTESTVQQCTATTAVPGPSPNPFHHTNWKELSRNEIIQSYLNLQSNVLNSSGVQAPSAHFFMSEYLKREEQEIKESRKMHVLQTDNLTGDLPGVSRDVTDEDLDRIHTQHWQGVNGVFDTKGTWYDWTDCISLDPHGDESKLNILPYVCLD
Length605
PositionUnknown
OrganismOreochromis niloticus (Nile tilapia) (Tilapia nilotica)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Cichlomorphae> Cichliformes> Cichlidae> African cichlids> Pseudocrenilabrinae> Oreochromini> Oreochromis.
Aromaticity0.04
Grand average of hydropathy-0.833
Instability index73.65
Isoelectric point7.67
Molecular weight66738.61
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29630
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     405.35|      68|      68|     254|     321|       1
---------------------------------------------------------------------------
   62-  127 (45.69/13.35)	.............KKTKDE...DLAKRAKKLLRNwqkliepGPPVAAsvPGS..TNG.S...SHPCRTDASPSDiS....VPGKgVPE.....VKIR
  131-  197 (72.58/24.79)	HNTYSPKAEKSSSR...........KRRAEHRDS.......GVYLQE..KIS..KMS.P.....YDNSVSTPPT.NgiagSPDA.LPDqevvpSPDR
  207-  253 (46.69/13.77)	KMNRIPVN.AVKPRPSS...............PG.......VAKLPS..TSSliKVA.V...MQQQARLDEGGG.G....Y................
  254-  321 (111.74/41.45)	YQARSPRGLTTSPRSTKQD...TMTKRSSAYAPK.......GTPVPS..PSS..RDS.P...LSFSHTVSSPAS.S....YADK.LPH.....SSNR
  325-  389 (72.80/24.88)	HWASSSEASSLCP...SQDisaTLE......SPS.......VSPSPS..LSQ..QNSePhrqMSEGAMVVSDDA.D.....GTT.VPN.....SEHK
  437-  480 (55.86/17.68)	EPSQTDEAPTPDPPESRQR...TESTVQQCTATT.......AVPGPS..P......N.P.....FHHT.............................
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29630 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PGPPVAASVPGSTNGSSHPCRTDASPSDISVPGKGVPEVKIRNDVHNTYSPKAEKSSSRKRRAEHRDSGVYLQEKISKMSPYDNSVSTPPTNGIAGSPDALPDQEVVPSPDRSRVEHLDNDKMNRIPVNAVKPRPSSPGVAKLPSTSSLIKVAVMQQQARLDEGGGGYYQARSPRGLTTSPRSTKQDTMTKRSSAYAPKGTPVPSPSSRDSPLSFSHTVSSPASSYADKLPHSSNRSSMHWASSSEASSLCPSQDISATLESPSVSPSPSLSQQNSEPHRQMSEGAMVVSDDADGTTVPNSEHKRRKYRSRDYSVNLDGQKMEDTTKPVRLKERRLTFDPVTGQIKPLVHKEPSQTDEAPTPDPPESRQRTESTVQQCTATTAVPGPSPNPFHHTNWK
86
483










Molecular Recognition Features






MoRF SequenceStartStop




1) LRNWQKL
77
83