<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29628

Description Uncharacterized protein
SequenceMVAGSALMEPSSKPGPNQVADVVFVIEGTANLGPYFESLRKNYILPAIEYFNGGPPAETDFGGDYGGTQYGLVVFNTVDCAPESYVQCHAPTSSAFEFVSWIDNIQFMGGGAESCSLIAEGLSVALQLFDDFKKMREQIGQTHKVCVLLCNSPPYLLPAVESVSYTGCTADSLVKIIRDRGIHFSVVAPRKLPPLRALFERASPVGGAVESLPDYSQDPFHMVLVRGISLPVSAGGGPGPHKPVIPPPVLASSQPVVGTPQPPPPINTTPPYQVMGKNTSLAAAQVAAQIVMEAANSQKNRLKPIPPNLSTVSTVNTPIQPVTPNQQPVPPPGQPVPSQPPQPLPQQPQPSGNQTTQPSAPPTMSSISVAPFSTSNPLLRPGSQVNPNPISQGQGVTNKVVAWTGVLEWQEKPKASSMDSATKLTRSLPCQVHVNPGENLNTDQWPQKLIMQLIPQQLLTTLGHLFRNSRMVQFLFTNKDVESLKGLYRIMANGFAGCVHFPHTTSPCEVRVLMLLYSSKKRIFMGLIPNDQSGFVNGIRQVITSHKQVQQHRAHYIRRAVGGKQLNSAAGPMQPNQVPPNQNFINRAPGPIPVSHGNVQQQMTMRAAGPTNQQPPVSGAPPNQVPTSGQAPPQGPILRLTNPGANPQLRSLLLSQQQPVRVHQSAVRMNYLVQGGVSHMPGMMSHQGLGQQMVHQAPGGGAQMQSQWRQPMAVFLPIPGQMMMSGAQRGAVPQPGMPQVSSMMEDEVLMDLI
Length753
PositionUnknown
OrganismOreochromis niloticus (Nile tilapia) (Tilapia nilotica)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Cichlomorphae> Cichliformes> Cichlidae> African cichlids> Pseudocrenilabrinae> Oreochromini> Oreochromis.
Aromaticity0.06
Grand average of hydropathy-0.243
Instability index49.27
Isoelectric point9.24
Molecular weight80852.95
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP29628
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     215.14|      42|      51|     189|     230|       1
---------------------------------------------------------------------------
  153-  184 (33.53/ 6.81)	......PPyLLPAVESVSY.....TGCTADSLVKIIRD.......RGIHF
  189-  230 (66.78/20.01)	PRK..LPP.LRALFERASP.....VGGAVESLPDYSQDPFHMVLVRGISL
  240-  281 (67.10/20.14)	PHKpvIPP..PVL.ASSQP.....VVGTPQPPPPINTTPPYQVMGKNTSL
  589-  629 (47.74/12.45)	P.....GP.IPVSHGNVQQqmtmrAAGPTNQQPPVSGAPPNQVPTSG...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     177.99|      35|      51|     306|     342|       2
---------------------------------------------------------------------------
  297-  336 (48.18/21.50)	.SQKN..R.lkpiPpnLSTVSTVNTPIQPVTP..NQQ..PVPPPGQPV
  337-  356 (32.74/ 8.58)	PSQPP..Q........................plPQQ..PQPSGNQTT
  358-  396 (49.50/17.31)	PSAPPtmSsisvaP..FSTSNPLLRPGSQVNP..N....PI.SQGQGV
  705-  738 (47.58/16.31)	QSQWR..Q.....P..MAVFLPI..PGQMMMS..GAQrgAVPQPGMP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.76|      26|      26|     472|     497|       5
---------------------------------------------------------------------------
  472-  497 (43.63/29.89)	VQFLFTNK..DVESLKGLY..RIMA....NGFAG
  499-  526 (36.73/24.04)	VHFPHTTSpcEVRVLMLLY..SSKK....RIFMG
  540-  571 (30.39/18.67)	RQVITSHK..QVQQHRAHYirRAVGgkqlNSAAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.34|      22|     243|     410|     452|       7
---------------------------------------------------------------------------
  410-  437 (28.79/18.71)	QEKPkasSMDSATKLTRSLpcqVHVNPG
  678-  699 (43.54/21.58)	SHMP...GMMSHQGLGQQM...VHQAPG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP29628 with Med25 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AVGGKQLNSAAGPMQPNQVPPNQNFINRAPGPIPVSHGNVQQQMTMRAAGPTNQQPPVSGAPPNQVPTSGQAPPQGPILRLTNPGANPQLRSLLLSQQQPV
2) GGGPGPHKPVIPPPVLASSQPVVGTPQPPPPINTTPPYQVMGKNT
3) QVAAQIVMEAANSQKNRLKPIPPNLSTVSTVNTPIQPVTPNQQPVPPPGQPVPSQPPQPLPQQPQPSGNQTTQPSAPPTMSSISVAPFSTSNPLLRPGSQVNPNPISQGQGVT
4) VSHMPGMMSHQGLGQQMVHQAPGGGAQMQSQWRQ
560
235
285
677
660
279
397
710

Molecular Recognition Features

MoRF SequenceStartStop
NANANA