<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29596
Description |
Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MLQDSSLNQIQQFLLPSVSNQPVNDLTIASPATASLASTPKTVNIINPTSSNIQQSEFIPHIFYSLYQITKDPNNSANQLETTTSSIKNKLKNCKKFIENDVNSINLLSKSIDEWEIYLKQRDQEIAVRQKLLSNLNLQITDILDENMDSQNNNEEKSSHRTITMDNPLIPENKELAVNNVEFDLAFAPKTNITADIAESEVKKTNGTASGINGINEASIYNDSIINTSNNDGENGQNNNINVNSIPNADDNNGVIDPTKMNDTNASPNTFSNEDISMTDI |
Length | 281 |
Position | Middle |
Organism | Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.634 |
Instability index | 41.08 |
Isoelectric point | 4.36 |
Molecular weight | 31048.76 |
Publications | PubMed=22123960
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP29596
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 106.17| 33| 38| 209| 246| 1
---------------------------------------------------------------------------
209- 246 (47.23/31.01) ASGINGINEASIYNDSiiNTSNNdgeNGQNNNINVNSI
249- 281 (58.94/26.78) ADDNNGVIDPTKMNDT..NASPN...TFSNEDISMTDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 77.17| 24| 24| 66| 89| 2
---------------------------------------------------------------------------
66- 89 (38.62/21.22) LYQITKDPNNSANQLETTTSSIKN
91- 114 (38.55/21.17) LKNCKKFIENDVNSINLLSKSIDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.88| 17| 146| 36| 57| 3
---------------------------------------------------------------------------
36- 57 (20.67/21.33) LASTPKTvNIinptSSNIQQSE
185- 201 (30.21/14.60) LAFAPKT.NI....TADIAESE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 46.95| 14| 24| 143| 156| 4
---------------------------------------------------------------------------
143- 156 (24.26/12.20) ILDENMDSQNNNEE
169- 182 (22.70/11.01) LIPENKELAVNNVE
---------------------------------------------------------------------------
|