<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29594

Description Uncharacterized protein
SequenceMLPTKYLLTPPEELHPYVPDYLRDTQAAIYPDFDPWQHTKDEDTIMTNFVSKGYYTTSKVNFESVSARSSLQDSLPKLTVQLASQFSNVVKLREEEVNRIPALPKNFEGTLFNDLSGPGFSLPTRITLTDHKRELWLQELSSSYASLSKISKYVPHGLKRRQVLEQCYMKQIPIKRAIWLIKCCYSLEWKSLMIKNQNKNENTNNINFQLLKDWTDNYVFIMEKLIFEMNTYSDDQIRLKVWKSEINYFLKLIGNCYSLNLLNKEVFHHWLVEFFSKVENFEFLPLTLHILTTFWDGICQPNNISDNSQPFFLVSKIVETLLQKYYQISNAKSMINDQKYIINDIKKNNSIKKAILNTIKSLVIKLFQTQSLEIFLFPNSSWDTYKPCLYEILNTNNDTSRMTNDIRRKLELVSYRNESLKFSIYPIEKSLGNDPANYFPAPDSNNEYITQLKSVDVKFTKLLDNNSIDYDWSTYIDRESFSVGHVLQLLIWTIHPSRKDHIDSIHLATKILLLRINSMEGSQEYVFEDTIWSLVFRISKIKPENRNSFVNLECLYRLLNLLIVYGIIKVPTYIRKLISSGILYLSDSTDKFFHCDVLINLNISPLTKSQYNMVLKNMMEYDTSYFENYTYDKLLVMSEELKQNLLNGQDDFDPESYPLSVKSMVSEWYLSYLCNGDLKMIDKGSLLRNFRIFKNKLEGSHHLYKWLEFIVYHQLMENIETLEALMDILMCNEKIFSQFINDHILFIKTFIFIYINILKVKDSDAYFVTSFMPFWKFVMKCFPVEITIDEDLRNKMSSVYENEKLKIEKLTKEKQLCYSIHDNLVNEKSEHNIKSNSPGSTPNNNSVTPTNRPSWNFTEIFQINIRILLGKNNSVQEQSRSRKIMLLLKGSNVREYNKFISIFLKRKDFKLYDLYFLIGSKLLTLEQIQKILGYEYIMQLISINSCEDSLEMITPYFEIHCFQFIVNNFQNISNFCIENLSKYYHQFLGILIPIGTRSGLARTSTKIIENLLNQSHINKTQFLEDALRYGTTSNIVNNDLECDIFEDDHTLDELNITNFYHKLDFTNLWLFQSFTSYQISILMKDEDGSYMDNLKIFLFELIDVCKGNCLCSQLLQQISNVDILRLIIHIFEKDFFEKCLSDLGIHSDDTVNTNFQNDNDEIYIPIKIIILLSQRISKISGSSEIKIDNEMFQLICQNIQKFYCLTEENLVHEGKRLEIFLKIFTLHQKSIFHYIVTCLQTNHKNRSNIIQTIKSLFQLFDKISFNLNLKLMLYEILSSLKSYIIYSSTIISDSEYHPVTSSSSVTSASSQNNTMTGNGNNNFHSTLNIPRDLLNLPPFQVSSFIDDKEKTNVSDDITLGITLLPCGTNNDNFTEDNMKKYYLYNVKDEVYESQLHNESYYNISNYQSDHGSSFNNSCLNLSLFNTAYERRNPK
Length1434
PositionKinase
OrganismTetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
Aromaticity0.12
Grand average of hydropathy-0.276
Instability index39.97
Isoelectric point6.05
Molecular weight168174.67
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29594
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     400.28|     148|     184|     502|     685|       1
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  395-  562 (95.48/102.01)	......................TNN.................................................DTSRMTNDIRRKLELVSyrnESLKFSIYPIEKSLgnD.....PANY.FPAPDSNNE.YITQLKSVDVkftKLLDNNSidydwstyidresfsvghvlqlliwtihpsrkdhidsihlatkilllRI..NSMEGSQEyVFEdtiWsLVFRISKIKPEnrnsfvNLECLYRLLNLL
  563-  729 (215.08/169.94)	IVYGIIKVPTYIrkLISSGILYLSDStDKFF............HC...DVLINLNISPLTKSQYNmvlkNmmeyDTSYFENYTYDKLLVMS...EELKQNLLNGQDDF..D.....PESYPLSVKSMVSEwYLSYLCNGDL...KMIDKGS..........................................llrnfRIfkNKLEGSHH.LYK...W.LEFIVYHQLME......NIETLEALMDIL
  740-  842 (89.71/44.95)	INDHILFIKTFI..FIYINILKVKDS.DAYFvtsfmpfwkfvmKCfpvEITIDEDLRNKMSSVYE....N....EKLKIEKLTKEKQLCYS.....IHDNLVNEKSEH..NiksnsPGSTP...............................................................................................................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     504.39|     154|     227|     859|    1020|       2
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  851-  997 (223.39/163.31)	...............NRPSWNFTEIFQI...NIRIL..LGKNNSVQEQSRSRKIM...LLLKGSNVRE.YNK..FISIFLkRKDFKLYDLYFLI....GS.....KLLTLEQIQKILGYEYIMQLISINSCEDSLEMITPYFE............IHC...FQFIVN....NFQNISNfciENLSKYYHqfLGILIPIGTR
  998- 1175 (212.45/142.83)	SGLARTSTKIIENllNQSHINKTQFLED...ALR....YGTTSNIVNNDLECDIFeddHTLDELNITNfYHKldFTNLWL.FQSFTSYQISILMkdedGSymdnlKIFLFELIDVCKGNCLCSQLLQQISNVDILRLIIHIFEkdffekclsdlgIHS...DDTVNT....NFQN......DNDEIYIP..IKIIILLSQR
 1177- 1248 (68.55/36.64)	SKISGSSEIKIDN..........EMFQLicqNIQKFycLTEENLVHEGKR...LE...IFLK..............................................................................IFT............LHQksiFHYIVTclqtNHKNRSN.......................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.03|      23|      61|     174|     196|       3
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  132-  156 (24.25/ 9.79)	.KRELW.........LqeLSSSYaSLSKISKYVPH
  174-  196 (42.68/22.70)	IKRAIW.........L..IKCCY.SLEWKSLMIKN
  237-  268 (33.10/15.99)	IRLKVWkseinyflkL..IGNCY.SLNLLNKEVFH
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.05|      29|     881|     355|     393|       7
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  355-  393 (40.32/50.72)	ILNTIKSLvIKLFQTQSLEIFLfpnsswdtyKPCLYEIL
 1249- 1277 (51.73/32.81)	IIQTIKSL.FQLFDKISFNLNL.........KLMLYEIL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.64|      35|    1072|     299|     333|      10
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  299-  333 (63.59/34.97)	CQPNN...ISDNSQPFFLVS...KIVETLL..QKYYQISNAKS
 1366- 1408 (51.05/26.65)	CGTNNdnfTEDNMKKYYLYNvkdEVYESQLhnESYYNISNYQS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29594 with Med12 domain of Kingdom Fungi
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