<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29578

Description Uncharacterized protein
SequenceMEDTKANINIKALLPKDCNISKLESSLAANPASHEALQRQLSQMQQQVLPLRLLFNNLLSILSGTNDTIADNEIYYSTVREMVVEISQQLQNISGNMAQLEPILSTVRSYNQEPNRSSFSQLLQNLSETKSLSQKFPQPIMTTASSNKRSKSQAATPISSTSNQNVNLSSVAPAPAKKPRKRQPKKQTTSSKKQNIQPSQQSQKSTPTALPIKSQKSAPPPNLNPTQFMAANSVSPTNVINTPVIATPLNGIKSPTVNSPQVNNNLIGSNDIFPGSNQHISMNNITPANILNTNLMSNNGNINNNSNNSNSNNSMNFNVNANMSHNNGSNNSTNNNNTNNSNNNNNNNNNHNNRSNISMGYNSNIANNNHTMHNANNSNSSASNHTNSNNNGNNNANNNNINSIDSSNLNLSNSNNGGNDLNLLDFNNIDFGNSLDFV
Length438
PositionTail
OrganismTetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
Aromaticity0.03
Grand average of hydropathy-0.878
Instability index56.39
Isoelectric point9.65
Molecular weight47505.27
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29578
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.13|      23|      24|     307|     330|       1
---------------------------------------------------------------------------
  307-  330 (45.44/13.05)	NNSNSNNSMNfNVNANMSHNNGSN
  334-  356 (45.69/10.60)	NNNNTNNSNN.NNNNNNNHNNRSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.70|      27|      27|     368|     394|       2
---------------------------------------------------------------------------
  277-  304 (41.41/ 9.73)	NQHiSMNNITPANILNTNLMSNNGNINN
  368-  394 (51.64/14.02)	NNH.TMHNANNSNSSASNHTNSNNNGNN
  397-  420 (42.65/10.25)	NNN....NINSIDSSNLNLSNSNNGGND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     148.81|      34|      34|      88|     121|       3
---------------------------------------------------------------------------
    9-   43 (23.15/ 6.99)	.......NI..KAllpkdcNISKLESSLAA.NPASHEA....LQRQLSQ
   88-  121 (61.68/30.94)	QQL...QNI..SG......NMAQLEPILSTVRSYNQEP....NRSSFSQ
  124-  153 (35.61/14.73)	QNLsetKSL..SQ......KFPQ..PIMTTASS.NK.......RSK.SQ
  191-  228 (28.36/10.23)	SKK...QNIqpSQ......QSQKSTPTALPIKSQKSAPppnlNPTQF..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29578 with Med3 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KSLSQKFPQPIMTTASSNKRSKSQAATPISSTSNQNVNLSSVAPAPAKKPRKRQPKKQTTSSKKQNIQPSQQSQKSTPTALPIKSQKSAPPPNLNPTQFMAANSVSPTNVINTPVIATPLNGIKSPTVNSPQVNNNLIGSNDIFPGSNQHISMNNITPANILNTNLMSNNGNINNNSNNSNSNNSMNFNVNANMSHNNGSNNSTNNNNTNNSNNNNNNNNNHNNRSNISMGYNSNIANNNHTMHNANNSNSSASNHTNSNNNGNNNANNNNINSIDSSNLNLSNSNNGGNDLNLLDF
130
426










Molecular Recognition Features






MoRF SequenceStartStop




1) LNLLDFNNIDFGNSLDFV
421
438