<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29577
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MNTTPLDEVQWQSPEWIQAFGLYTDNVLDYFSESPFFNKTSSNQSIRMQRQFQADANGAGPGAGQGPDMLGVLDPHHNETDKLLLQHVRDPERRAILTRYPVHAQLERQLAKVGGIEYVLAHVREPDLWVIRKQRRDIQTMNTSILQTYYVMGPSVYQAPSIHALIESRLLAASTGLEKTMVGLRKLARFEPAQGRYLVRNGTVTSSSSTVSESGGSGKTVPNTGPATGSNGAYSIPGSGFPGSAAPGTTVAGQTAGGTAQFESNRRPAAALSTSQLDKLLAVSFKARPEYI |
Length | 292 |
Position | Head |
Organism | Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 77-7) (Yeast) (Kluyveromyces blattae) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Tetrapisispora.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.411 |
Instability index | 43.36 |
Isoelectric point | 9.07 |
Molecular weight | 31678.18 |
Publications | PubMed=22123960
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 PIRNR:PIRNR013286
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coactivator activity GO:0003713 IEA:EnsemblFungi
|
GO - Biological Process | positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly GO:0051123 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP29577
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 105.97| 30| 32| 192| 221| 1
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192- 221 (50.73/30.36) PAQGRYLVRNGTVTSSSSTVSESGGSGKTV
222- 251 (55.23/33.69) PNTGPATGSNGAYSIPGSGFPGSAAPGTTV
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