<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29572
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MPSAARRQRQITPTSPSPSPEPQQGTANGTTTTTSHAAPQQSSPQPPSSNAHPQTSDSSDPTSAVRANLETRVRSVVDLLYQLAVCSADVQEGSQHLVANKVNECIKALAALDATKEELHRAHLMVPQDVLEMLDAGKNPDIHTRNFVNRLASENQYSYGQHTAVERYKDKLDAALDEAFPELKVAPRGD |
Length | 190 |
Position | Middle |
Organism | Ustilago hordei (strain Uh4875-4) (Barley covered smut fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina>
Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Ustilago.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.709 |
Instability index | 54.23 |
Isoelectric point | 5.78 |
Molecular weight | 20601.52 |
Publications | PubMed=22623492
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP29572
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 100.96| 26| 63| 95| 122| 1
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95- 122 (37.27/33.27) QHLVANKVNEciKALAALDATKE.ELHRA
123- 143 (23.71/13.86) HLMVPQDV......LEMLDAGKNpDIH..
161- 186 (39.99/27.49) QHTAVERYKD..KLDAALDEAFP.ELKVA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 85.27| 23| 28| 9| 33| 2
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9- 31 (42.46/21.58) RQITPTSPSPSPEPQQGTANGTT
40- 62 (42.81/16.81) QQSSPQPPSSNAHPQTSDSSDPT
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