<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29570

Description Related to SSN3-cyclin-dependent CTD kinase
SequenceMHSTSASSSSADYIRPSGYFYDDADDPFAGAFWPQFEDPHDLAAKHIPTDSSPAAAMRAYREYRDRVRKPVLATYTILGFLSSGTYGRVYKARLRSAPQVSSSSVPPAIGYGGGVGGGGGVGRDAGGRDAGPGSGVATGGGGATAKKHAGLLQQHQLLDLPSAASCLDATSKSLAEGAGDKATSSGLGDSSPSLATSSGAAVPAALGGTDHSAQLANAIPDGQVYAIKKFKPDTKETDATIYTGISQSAMREISLNRELCHVNIVTLHQVMLEDKAIYMVFEYAEHDLLQIIHYHSTALRAPIPSAVLKSLLWQLINGVAYLHANWILHRDLKPANILVTSQGVVKIGDLGLARLYSSPLQSLYNGDKVVVTIWYRAPELLLGARHYTTAIDMWSVGCIWGELLALRPMFKGEEAKVDPKTKAAPFQTDQLKRIVEVLGTPNKDRWPAIESMPDYKGWWPHLRLDNYPKTLSRWYTTRNKGDDGYDLFDSLLQYDPEQRLTANQALEHGWFTWQDPKPTANAFVSLAKPIGTYPNRRVIQDDLDPKMISNYLPPIDSHHLAPSHQFNLNSSHPHRLAQLLHQQEQLRHQQMQSQQPLQQQPPPTTAVAAARAAAPVAPPVGGPAAPPPITIGSANTGGAGAGAAGGAGGAGGAGGAGGAGGGAFAFSSAAPSTAPSHTLQNPVIRIAGTSGATYSNPASVTSVQSVASTEAGSATDTPTTVGTGTGVAARNANNLVATATRNQQRKRQRI
Length750
PositionKinase
OrganismUstilago hordei (strain Uh4875-4) (Barley covered smut fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Ustilago.
Aromaticity0.07
Grand average of hydropathy-0.309
Instability index48.03
Isoelectric point8.75
Molecular weight79352.06
Publications
PubMed=22623492

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29570
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     137.35|      22|      22|     621|     642|       1
---------------------------------------------------------------------------
  101-  122 (34.97/12.02)	SSSSVPPAIGYG.G.GVGGGGGvG
  126-  143 (25.26/ 6.80)	GGRDAGP....GSGvATGGGGA..
  621-  642 (43.34/16.52)	GGPAAPPPITIGSA.NTGGAGA.G
  645-  662 (33.79/11.38)	GGAGGAG....GAG.GAGGAGG.G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.11|      17|      18|     187|     203|       3
---------------------------------------------------------------------------
  167-  183 (25.87/12.94)	LD..ATSKSLAEGAGDKAT
  187-  203 (29.77/16.05)	LG..DSSPSLATSSGAAVP
  206-  220 (18.48/ 7.07)	LGgtDHSAQLAN....AIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.77|       9|      25|     370|     381|       4
---------------------------------------------------------------------------
  370-  381 (11.58/12.68)	VVTIWyraPELL
  396-  404 (18.19/ 9.37)	VGCIW...GELL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.40|      10|      26|      61|      70|       6
---------------------------------------------------------------------------
   61-   70 (19.37/11.40)	REYRDRVRK.P
   88-   98 (14.04/ 6.56)	RVYKARLRSaP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.95|      27|      35|     668|     696|       8
---------------------------------------------------------------------------
  668-  696 (39.51/26.54)	SAAPSTAPSHTlQNPVIRIAGTsGATYSN
  705-  731 (45.44/22.63)	SVASTEAGSAT.DTPTTVGTGT.GVAARN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.07|      10|      22|     567|     578|       9
---------------------------------------------------------------------------
  567-  578 (13.12/13.08)	NLNSSHPhrLAQ
  590-  599 (18.95/10.06)	QMQSQQP..LQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.61|      13|      25|     445|     458|      10
---------------------------------------------------------------------------
  445-  458 (23.22/19.78)	RWPAIESMPDyKGW
  473-  485 (26.39/16.29)	RWYTTRNKGD.DGY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29570 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HLAPSHQFNLNSSHPHRLAQLLHQQEQLRHQQMQSQQPLQQQPPPTTAVAAARAAAPVAPPVGGPAAPPPITIGSANTGGAGAGAAGGAGGAGGAGGAGGAGGGAFAFSSAAPSTAPSHTLQNPVIRIAGTSGATYSNPASVTSVQSVASTEAGSATDTPTTVGTGTGVAARNANNLVATATRNQQRKRQRI
2) YGGGVGGGGGVGRDAGGRDAGPGSGVATGGGGATAK
559
111
750
146










Molecular Recognition Features






MoRF SequenceStartStop




1) ADYIRPSGYFYDD
11
23