<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29347

Description Uncharacterized protein
SequenceMPSPYSTSSSPGYHSPNVHRNATNIPLKKYTLQPPPRKLPLSKTMPSLGYPDMFPQRPGQDEDVLSESNIRQGFIDRPIVSNENSSAHDIVFGKLQEDQRALSDLSDFIVDVLHRQNRASYITGPSSFRPPVRTTLIDAKREQWMHELSSGVVPLKQLAKNVPHGFKGEKLLETLATKQVPFLRATWYIKIVGLSEMSQRNASNAAASMGPQSIQWTTIVTNHLKKQLNELVPSPHTSNSNNAAIPHAAGTPNRGYRNYSNHHENSAKPWLTPESRARFEQRWSYSVQLARWQYYEGLIDQKTFLRWSLDTLSDCTSFEVIWVMLTGLIQDYVDEYKRNRTLTKILIETLIRFYSALQQYINHNTLEETDQRVHQGLQKDIETVLQSLFLSAPDMFVIPKLYQQYHHLLNVIIGEEATSRSTKASSDMRRVMNEYWAMIKARNETFCGKVDKSPVGQKTSQSTHESGGGDEERIVTLLDSIGKNIDSVSGLQINGETWTDAHGHSAKWASKTIFDGEVDPESMSCDEDEAFRIEGEEDHTKRPNVHIVYLYDVLIRSSLFSYQKYLLRLIARGDLEPRRRNEHTIQQRLHYLASFPLLTPAPAYLINQRRVALYGTRNDSNNKETETEALNDLKHLARLAVMGFDHHNTDCLFGINAQDMTQPVPADTFESYNLAFSQELKHKLMSTMDSTTRYSVLEFTSHWLLNEVKKFVVKSIQIGEDNWRVMTSPGSCLLNTRQLVTIIQIMECAKDYLSIIEMALWVLQKSNDTSLHPYIIDTFRKYSCYWKLTNNSARVIQAVWTKHVNLCSRGERDRNIMMYMVQLVQEGYQMDDLSRSQLQQDLQIKSKTRSHYTNNLSVKSELMQLTKDFHVSSIQMVAESLSLPSQNAAGWIGIILENAGDVLRMIGKEKGIDKEIKSYRHGRFLSQALFEFHRMLRTFALIIKQVVNATILTGQADNAVIYWLWNNEVVQEDMYQENSWVPLFVITLVANNVIALDTLIKSFAIPWFERIGQEGQQQFCSEDTKLNVFCQNLIVLIRLLVIQNDNEPKSEEASLSWPLRIEEFFQLEVQRQMNLASSLDRIDPLFGLMERMILIATNLPLSSSLLQDLVMLRADLLQISWFRQACLRDLNGVYQRFASREAEAVTEKRLKKKMLSIVEELIGGDLVASQSIIQDTAPNFIDKLHKVFLNVSQWNEAQCRVQMNLLLDNISLYDVNSQNPNNPHILGDDLSMDITSDICVSPSNKDLQSFVSFFYDVVLADGHFERAATQRRFQFFKNLIHELRKPVLSELLAHAVRLLEGDPSQAFPDSVLLMPSSEQHAPFDSNTFAYRSQAFLNMTQHMLAENVWPNEKKVDLVKTVFRQILRFRDSLSVYKVMQSVNICYAEASAALQATKNNTDMAITMLLTEGSLESTLVEMDHERKLSLQDIRTRLRLIVPYMSLIWEHPKEDECDILDWIRTLVQLLGSPLVHGNGSQERFFEFILDFVSILIDGVFSELPRELKRASLQLLNSMQHELSSVPEMFQGRVKRIMPFTAHNIYLNNTHLASSILGLQSSDDAQQQQQHLEACLEQSKPWEWLEDYVNETPHDNDAPISLTIFNALKPKSVDSTYIKWFKYGFDTGNTSQPTQ
Length1629
PositionKinase
OrganismRhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar)
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Mucorineae> Rhizopodaceae> Rhizopus.
Aromaticity0.09
Grand average of hydropathy-0.352
Instability index50.00
Isoelectric point6.06
Molecular weight186878.51
Publications
PubMed=19578406

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29347
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     509.56|     166|     547|     773|    1057|       1
---------------------------------------------------------------------------
  254-  436 (256.89/126.35)	RGYRNYSNHHENSAK....PW...LTPESRARFEQR.WSYSVQLARWQYYEGliD.QKTFLRWSLD....TLSDCTSFEVIWVMLTGLIQDYvdeykrNRTLTKILIETLIRFYSALQQYINhNTLEETDQ..RV...HQGLQKDIETVLQSLFLSAPdMFVIPKLYQQYHHLLNVIIgeEATSRSTKASSdmrRVMneYW
  780-  963 (252.67/316.87)	RKYSCYWKLTNNSARviqaVWtkhVNLCSRGERDRNiMMYMVQLVQEGYQMD..DlSRSQLQQDLQikskTRSHYTNNLSVKSELMQLTKDF......HVSSIQMVAESLSLPSQNAAGWIG.IILENAGDvlRMigkEKGIDKEIKSYRHGRFLSQA.LFEFHRMLRTFALIIKQVV..NATILTGQADN...AVI..YW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     285.33|      90|     475|     630|     725|       3
---------------------------------------------------------------------------
  630-  725 (141.86/109.19)	LNDLKHLaRLAVMGFDHHNTDCLFGINAqdMTQPVPADTFESYNlafSQELKHKLMSTM......DSTTRYSVLEFTSHWLLNEVKKFVVKSIQIGEDNWRV
 1106- 1201 (143.47/92.71)	LQDLVML.RADLLQISWFRQACLRDLNG..VYQRFASREAEAVT...EKRLKKKMLSIVeeliggDLVASQSIIQDTAPNFIDKLHKVFLNVSQWNEAQCRV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29347 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MPSPYSTSSSPGYHSPNVHRNATNIPLKKYTLQPPPRKLPLSKTMPSLGYPDMFPQRPGQDEDVLSES
1
68










Molecular Recognition Features






MoRF SequenceStartStop




1) HRNATNIPLKKYTL
2) TYIKWFKYGFDTGNT
19
1610
32
1624