<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29342
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MESEPTAKRVKLSLEPFIDNKILDITNSGHEIPKTEIPLAEKMMQTVDRIWFERGEWKDITEQSLQESTLVDKEEKDVKNDEQIESQEQQQVVPPGFDVVKLRESVINKLLHAKSEIDVALDVINILAASHHASTAKDLVLPAGSLSATYVTKPKSTMKAELEAVQLNLGLKRKQQKQASDYLKKSASALNSIIEKEHEFWDEALNLRRHNWIMYANTTHPNNSFLIQYGFAEVGSDFNEASLGELKRADDGVQLSVAHDQPRRVTVHTRHANSLLGMEDQVKDDEKAYYEPEAKEIQNQLMQATSTVFDAELFSNILAEAQTLNSNVRIGNDEIEINIDGDINLSITKLPVTSTIESYQDNKICMTNLAFRLLLLQRYDFNMWKNKARILSTNHIIQNSLAKKSDTGTSSTNTSTSNHHSAVISRARNRVELPKTVAILSPVLSISRFWAQFDRIRQVVHSILYPFRRLGFSVHYKILTDNNSNNLHPSCGKMSLYFNIGLNKGSHLQFALNQQSGTISVILPQATVVLQHVSELRAFLSREINIMCLGFICDVANDIIQIHPHSAQKMLLWKLDRIDEVIHSSLCTKEDQWKHINVQLFHDATSFHVQFIVTNETKEEKVFIKDTQEYSAMTFKEKVSKIIQEMMGDD |
Length | 650 |
Position | Head |
Organism | Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina>
Mucoromycetes> Mucorales> Mucorineae> Rhizopodaceae> Rhizopus.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.389 |
Instability index | 47.20 |
Isoelectric point | 6.02 |
Molecular weight | 73933.09 |
Publications | PubMed=19578406
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP29342
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 37.34| 15| 21| 47| 67| 1
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35- 60 (15.89/33.09) TEIPLAEkmmqtVDRiwfergEWKDI
61- 78 (21.45/16.15) TEQSLQE..stlVDK......EEKDV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 60.60| 19| 286| 97| 142| 2
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118- 141 (25.66/61.35) DVALDVINIlaashHASTAKDLVL
554- 572 (34.94/ 7.96) DVANDIIQI.....HPHSAQKMLL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.52| 14| 120| 450| 464| 7
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450- 464 (23.59/18.49) WaQFDRIRQVVHSIL
573- 586 (26.93/16.33) W.KLDRIDEVIHSSL
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