<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29324

Description Heat shock 70 kDa protein 18
SequenceMAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPVNTVFDAKRLIGRRFSDASVQSDMKFWPFKVTPGQADKPMIFVNYKGEEKQFAAEEISSMVLIKMREIAEAYLGSSIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKKATSVGIKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGDARALRRLRTACERAKRTLSSTAQTTVEVDSLFEGIDFYSPITRAKFEEMNMDLFRKCMEPVMKCLRDSKMDKSMVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGIETIGGVMTTLIQRNTTIPAKKEQEFTTTVDNQPDVLIQVYEGERARTIDNNILGQFVLSGIPPAPRGIPQFTVCFDIDSNGILNVSAEDKATGKKNKITITNDKGRLSKDDIEKMVQEAEKYKSEDEEHKKKVEAKNGLENYAYNVGNTLRDMGEKLPAADKKKFEDSIEEVIQWLDDNQLAEADEFEHKMKELESVWSTIITKMYQG
Length617
PositionUnknown
OrganismArabidopsis thaliana (Mouse-ear cress)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Camelineae> Arabidopsis.
Aromaticity0.07
Grand average of hydropathy-0.367
Instability index35.96
Isoelectric point5.22
Molecular weight68355.92
Publications
PubMed=11130712
PubMed=27862469
PubMed=17147637
PubMed=11599561
PubMed=11402207

Function

Annotated function 
GO - Cellular Component
chloroplast envelope	GO:0009941	IDA:TAIR
cytoplasm	GO:0005737	IBA:GO_Central
cytosol	GO:0005829	HDA:TAIR

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
response to cadmium ion	GO:0046686	IETAIR
response to heat	GO:0009408	IETAIR









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29324
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.79|      35|      40|     497|     536|       1
---------------------------------------------------------------------------
  497-  535 (48.58/39.28)	EDKATGKKnkiTITN...DKGRLSKDDIEKMvQEAEKYKSED
  539-  576 (53.20/27.16)	KKKVEAKN...GLENyayNVGNTLRDMGEKL.PAADKKKFED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.81|      18|      21|      38|      55|       2
---------------------------------------------------------------------------
   16-   33 (19.07/ 8.98)	....TTYSCVGVWQHDRveIIA
   38-   55 (32.55/19.62)	NR..TTPSYVAFTDSER..LIG
   60-   78 (24.19/13.02)	NQvaMNPVNTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.24|      18|      41|     337|     356|       3
---------------------------------------------------------------------------
  337-  356 (25.55/24.37)	VHDVVLVGGSTRipKVQQLL
  381-  398 (29.70/19.87)	VQAAILSGEGNE..KVQDLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.61|      13|      17|     203|     215|       4
---------------------------------------------------------------------------
  203-  215 (22.69/13.64)	IFDLGGGTFDVSL
  222-  234 (21.92/12.94)	IFEVKATAGDTHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.82|      23|      43|     426|     448|       5
---------------------------------------------------------------------------
  426-  448 (38.38/23.22)	IPAKKE..QEFTTTVDNQPDVLIQV
  470-  494 (37.44/22.49)	IPPAPRgiPQFTVCFDIDSNGILNV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29324 with Med37 domain of Kingdom Viridiplantae
Unable to open file!