<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29316

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGRAEECIGLCRALMSALNWLLRCAAFYAEKVKEMLEQVAAEGQMKMCLERLEKMLSSTKNRALIHIAQLEETSSWNAVEQSLLKLEESLNGLSNSTLRSQADDCISLIKSIPTMLSVRSEQLNKTGFPTVHAVVLLEGTMNLTGEIQPLVEQLMMVKRMQRIPSPLFMLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVELKNYPHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCNCMSLLLQECSKQGLLSEANMTNLTDKRKADREDAPQLQSAENANIQPNPRLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFAWKFIKLNEFTKHISTENSKSAPVRALLFDISFLMLCHVAQTYGSEVILSESRPADEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQINWHEVCLSISAAILEILNAWENSVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYGDNTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTSVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLTLLGHILPNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASARQKKRHREDIEDYISLFPLDDTRPSKLMRLLSSNEEDANILSSPNRSMSSSLSASQLHAVSMRDPLNRVLANLFLLISSILGSKTAGTHTQFVQWFMEECVDCLEQGSHGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLGLPLGRRVAAKAIAAL
Length986
PositionTail
OrganismGallus gallus (Chicken)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Galliformes> Phasianidae> Phasianinae> Gallus.
Aromaticity0.07
Grand average of hydropathy-0.004
Instability index50.53
Isoelectric point6.24
Molecular weight110846.98
Publications
PubMed=15592404

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29316
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.21|      42|     194|     701|     773|       1
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  701-  749 (62.09/78.84)	KKPIKEVLTSVFtkVLEKGWVDSRSIHIFDTLLHmggvyWFCNNLVKEL
  891-  932 (73.12/32.19)	RDPLNRVLANLF..LLISSILGSKTAGTHTQFVQ.....WFMEECVDCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.26|      27|     194|     321|     369|       2
---------------------------------------------------------------------------
   87-  121 (43.56/16.26)	DFSRDL.C.......VQSLLEIMDMFCDrlsCHgraeeCIGL....C
  326-  364 (37.70/65.03)	DFTEDVnCafefllkLTPLLDKADQRCN...CN.....CMSLllqeC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.87|      21|      32|     146|     166|       4
---------------------------------------------------------------------------
  146-  166 (34.94/21.58)	LEQVAAEGQMKMCLERLEKML
  180-  200 (32.93/19.92)	LEETSSWNAVEQSLLKLEESL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.89|      43|     813|      31|      83|       9
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   31-   83 (64.01/63.27)	FPRGATW..DILNLAEALLEQAMIGPSPNPLILSYLKyaiSSQmvsystvLTAIS
  845-  889 (68.88/43.98)	FPLDDTRpsKLMRLLSSNEEDANILSSPNRSMSSSLS...ASQ.......LHAVS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29316 with Med24 domain of Kingdom Metazoa
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