<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29309

Description Uncharacterized protein
SequenceMHAVNEIISILEKINITKELLETTRLGKHVNELRRKTSDPTLARRAKVLVKRWRDLVIPVASPGHTAWGGYESDSQDVILVDDDPPPPPAVVPHKPVTPPVKRPPSVEAVYDEKKAKRDKKPKKKRVHSRAGSGSETTAEPGWGARNGAAPHRRNGTRPPDPYAALVHRLPPAGGKKVKTTKELLEQIQSRGKPLSPGSPVASPPDSPDVMLIEPER
Length217
PositionUnknown
OrganismBombyx mori (Silk moth)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Bombycoidea> Bombycidae> Bombycinae> Bombyx.
Aromaticity0.03
Grand average of hydropathy-0.787
Instability index72.45
Isoelectric point9.99
Molecular weight23790.02
Publications
PubMed=19121390

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP29309
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.73|      29|     162|      12|      40|       2
---------------------------------------------------------------------------
   12-   40 (48.67/28.49)	EKINITKELLETTR.LGKHVNELRRKTSDP
  176-  205 (46.06/26.59)	KKVKTTKELLEQIQsRGKPLSPGSPVASPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.39|      20|      21|     113|     132|       3
---------------------------------------------------------------------------
  113-  132 (32.59/16.62)	EKKAKRDKKPKKKRV.HSRAG
  136-  156 (27.80/12.95)	ETTAEPGWGARNGAApHRRNG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP29309 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) YESDSQDVILVDDDPPPPPAVVPHKPVTPPVKRPPSVEAVYDEKKAKRDKKPKKKRVHSRAGSGSETTAEPGWGARNGAAPHRRNGTRPPDPYAALVHRLPPAGGKKVKTTKELLEQIQSRGKPLSPGSPVASPPDSPDVMLIEPER
71
217

Molecular Recognition Features

MoRF SequenceStartStop
1) AKVLVKRWR
2) KKPKKKRVHSR
3) MLIEPER
4) PYAALVHRLPPAGGKKVKTTKELLEQIQSRG
5) VEAVYDEKKAKR
46
120
211
162
107
54
130
217
192
118