<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29300

Description Uncharacterized protein
SequenceMGIMYEKRPLKRPRLGPPDVYPQEPRQKEDELTSTNIGQFFSGILSKKEELNTLPDCGRKRQQVNPKDNFWQATARTKPQIEVWFKDLAGNKPLAQLAKRAPNFNKKEDIFITLTEYQVPMPRAAWFIKLSSAYTVAVSEAKIKKRQLPDPTTEWTTTLIKFLKDQIPKLSEYYQSVAPGNISDKTPPSQSGPGTPSHNSSGNAPGNSTPNSTVPNSLHSPGNSANMGSSTPGNESTDWRQALKLWHYCCRLAKYLLDEGLLDRHDFLTWVIELLDKRMPDDGLLRLFLPLTLQHMNEFVDCEGLSRRLATTCAKKAAAICSVLSEATLRALNQPAVFNRPAEKSTESNTQPMSPAPESNGDVKPNIAQIKRSGTPAEQSQGTPNPNHSMGTPNPNHSIGTPNPQQPMEVQGKEDSVSPPRDVKTTVNTVINASMNPVQVGFGEILNCSFHRDVIIQLATILQVICVDCPTAMVWSGCGSSLQGSPLDLLPVPPSSLPMPHMDSEITEEHRRLVYEAEQEISARSKKAESKWCTDKWQTSSQARVLAVLEALDRHCFDRVDPNNNLDTLYKEVFINCTPPSKDGAIDTKDPEWACSYAVVRVLCEWAVCGARWGEHRALAAAALLDRRQQQLQHLHHDHHATGSDDKESVSSGTGICSGPPIFQNLLLRFLDNDAPVLDESPNAPPGNRQQFANLVHLFGELIRRDVFSHDAYMCTLISRGDLISPTEPTSTIGNSIQTVAPPASSSGTNHNVNDEIFAGIDLKPKMEENVRMDLDDSRIDDDLDKLLQHIKEDQQNSMDAPDSPKDPGETSHSVNSPMMGPGGMTIPGIPSIGMGPMSVPGIRTGSAGPSSAGGCAAASRHYHYTMHFPLPPAEPDHAPHDANQRHILLYGVGRQRDEAKHAVKKMTKEICKLYSKKFSIDVAEGGKIKKHSRSEFNFEAVTQKFQAMSMYEQGAVSWAVGGAVCEALAAYAAGATTYLPQPEHVAFALDLMEIALNVHGLIETCIQILKELSEVEGVLITRGTPSSGIATPRAYTSALALYTVGALRRYHSCLLLCVEQTSAVFEQLCRLMKSVGNPDDCGSAERCVLALLHDLYKAAAHLCHAPHADTFANAYPKIKQALYSPLQPIPSNYVYNPEFLSDFFTNPRKVSTSPGPGGAAAGVRLSCDRHLLAAAHKNIGVAPVLATLKAILMVGDSARDGGKIGKKSCELSHILGTSDAVPSDAQLDLLSGGGGVGSSLLDSSQSLSSFARKVLAEICSEEWVLQKCLQNPDELYQTGMLLDSMITPKQAQRLLHMICYPDSASHTHPDLDQKTMITRLLENLEQWSLRMSWLDLQLMFKQFPGGSPELSAWLDTVARAIINVFQQPAPPPPDKDRMGTDRGVVSTSKWSDSVWLVAPLVAKLPPAVQGRVLKQAGQILENGWGAGCSGNCAGGSGGGGGSHRDCKSHQSPSYKGSSTGGSGGKRGVSSGACGGGCACGGSNAVRLANEPLLSLVLTCLRNQDDQKESLLSSIHAQLQHYLTHARDHERSACNDTWHDEVAPEALQLRFSLAGGMFDAIRRSYQLTSDWAVLLTQLVAHQVVDAYNNSNLFNTLIDMLATLIHSTLADGGDDNNRKHYQNLMKKLKKEIGDRHGPSVQCVKQLLPLSKNTIIEVIACEPLGCLVDQKGNKITGFDSDKKQGLRLTEKQRVSVWELVEGGRNPAPLSWAWFAATKIERKPLTYENAHKLLKFHTHSMVKPLSYYLEPLPLPPEDLETNDNKQDNESLESSPTGAGKSRSRSVSGKNIKKMKPSTPTNSLNGNGMAGGPSNMAPATAQQPQFMHQQQQWFPPPGQNYYNQPAGVNTRGVAPPSNTQSKQALSNMLRQRVPFNQMTQMQQGTGYPAAPHRGPFPPRQSIRPMQPNQMGTMQAQQMNPMGGMGGMGPMNQMGGVQMPAQMAGGQMSSAPMGGAQMGAGQMGGMGGQMFGGQYGGMQQSYAGYGQQMMQGGQQQMMSQGMGQSVSQMGQQVNAMGQSVNSMGQNVPQMNQGVGQSAQMPQGMSQMNQSMAQMGQPMSQMGQMGQATGMGGMNTQAGSMGPQAGNGMGAFAGQQSFQQNMMGGRATQEAYLAQQRQTARPPYMQQAPNVTMGGMGGPAPPYPRGMQPQQSTQYQQQMTQQRMRQQMLAMQQQQQQGPLVQHLQRQQQYQPPY
Length2188
PositionKinase
OrganismBombyx mori (Silk moth)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Bombycoidea> Bombycidae> Bombycinae> Bombyx.
Aromaticity0.06
Grand average of hydropathy-0.490
Instability index52.13
Isoelectric point7.65
Molecular weight238087.44
Publications
PubMed=19121390

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29300
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.75|      15|      17|    2055|    2071|       1
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 2028- 2044 (16.48/ 6.19)	GvgQSAQMPQ..GMSQMNQ
 2045- 2061 (24.27/ 6.66)	S..MAQMGQPmsQMGQMGQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.32|      17|      18|     374|     390|       3
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  373-  389 (33.69/16.77)	SGTP.AEQSQGTPNPNHS
  390-  407 (30.63/14.39)	MGTPnPNHSIGTPNPQQP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.49|      17|      18|     191|     208|       4
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  178-  203 (22.29/12.18)	APGNI..sdktppsqSGPGTpSHNSSGN
  204-  230 (25.19/ 9.26)	APGNStpnstvpnslHSPGN.SANMGSS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.23|      14|      19|    1925|    1943|       5
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 1929- 1948 (17.87/ 8.34)	MGGvQMPAqmAGGQMssaPM
 2158- 2171 (23.36/ 7.93)	MRQ.QMLA..MQQQQ...QQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.90|      17|      19|    1429|    1445|       6
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 1429- 1445 (36.72/18.28)	C....SGNCAGGSGGGGGSHR
 1447- 1467 (26.18/10.63)	CkshqSPSYKGSSTGGSGGKR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.49|      15|      18|     818|     832|       7
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  799-  812 (20.54/ 7.57)	.MDAPDSPKDPGETS
  818-  832 (31.47/16.77)	PMMGPGGMTIPGIPS
  837-  851 (27.49/13.42)	PMSVPGIRTGSAGPS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     130.80|      18|      18|    1854|    1871|       8
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 1816- 1830 (25.36/ 8.32)	TAQQPQ...FMHQQQQWF
 1854- 1871 (25.15/ 8.18)	NTQSKQALSNMLRQRVPF
 1910- 1926 (30.45/11.75)	QAQQMNPMGGM.GGMGPM
 1967- 1980 (23.96/ 7.38)	GGQY....GGMQQSYAGY
 2107- 2124 (25.88/ 8.67)	LAQQRQTARPPYMQQAPN
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.63|      15|      22|     252|     273|       9
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  252-  268 (22.40/27.67)	LAKYLLDEGLLdrHDFL
  275-  289 (28.23/11.26)	LDKRMPDDGLL..RLFL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.95|      16|      19|    2064|    2079|      10
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 2064- 2079 (33.40/13.20)	GMGGMNTQAG....SMGPQA
 2082- 2101 (24.37/ 7.55)	GMGAFAGQQSfqqnMMGGRA
 2126- 2144 (22.17/ 6.17)	TMGGMGGPAPpyprGMQPQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.49|      18|      23|    1327|    1349|      11
---------------------------------------------------------------------------
 1312- 1329 (27.93/ 9.74)	LDQKTMITRLLENLEQWS
 1335- 1352 (31.56/27.52)	LDLQLMFKQFPGGSPELS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.86|      14|      18|     111|     124|      14
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  111-  124 (26.43/16.20)	FITL.TEYQVPMPRA
  127-  141 (16.43/ 7.07)	FIKLsSAYTVAVSEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.29|      13|      18|     947|     959|      15
---------------------------------------------------------------------------
  947-  959 (24.94/15.15)	QAMSMYEQGAVSW
  967-  979 (21.35/11.84)	EALAAYAAGATTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.01|      17|      17|     552|     568|      16
---------------------------------------------------------------------------
  531-  553 (22.73/11.38)	KWCTDKWQTSSQarvlavLEALD
  554-  570 (31.29/18.67)	RHCFDRVDPNNN......LDTLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.78|      44|     179|    1354|    1404|      17
---------------------------------------------------------------------------
 1354- 1404 (70.34/66.92)	WLDTVARAIINVFQQPAPPPPDKDRmgtdRGVVSTSKWSdsvWLVAPLVAK
 1538- 1581 (78.44/53.96)	WHDEVAPEALQLRFSLAGGMFDAIR....RSYQLTSDWA...VLLTQLVAH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.05|      15|      18|     689|     703|      19
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  689-  703 (27.41/22.64)	RQQF...ANLVHLF..GELI
  705-  724 (18.64/12.28)	RDVFshdAYMCTLIsrGDLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.32|      15|      21|     877|     891|      22
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  877-  891 (28.85/21.45)	DHAPHDANQ..RHIL.LY
  898-  915 (17.47/ 9.54)	DEAKHAVKKmtKEICkLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.10|      28|      30|    1177|    1206|      23
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 1177- 1206 (42.55/38.57)	HKNIGVAPVLATLKAIlmVGDSARD....GGKIG
 1207- 1238 (43.55/31.41)	KKSCELSHILGTSDAV..PSDAQLDllsgGGGVG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.51|      16|      19|     762|     778|      24
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  762-  778 (22.64/20.40)	DLKpKMEENVRMDLDDS
  783-  798 (26.87/17.69)	DLD.KLLQHIKEDQQNS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29300 with Med12 domain of Kingdom Metazoa
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