<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29299

Description Uncharacterized protein
SequenceMKEVAAGSTATTSNSSNSGSACSVALSFHLAGARRCTPEECEEETPSPANNNQPPPTAARAFLKLHSLVELDTFTLTHGPFTPLDTPGMQPGKRKLSSPNARSVRVRQPAYFLPELAHVVAAADERVPFVNLAQELSSRGVSHGGVQGEWSGSALGMRLVSLPLPEGASVAAGSALRARLLATTVRLTTKNQARVWTAEIVFHGSPLRTPNPKEQGERRCVYLQYELGTDAGRTAEAFLADWAAIVHLHTLLHDFMLRPAQERESLWQGVFIRSYTYRSLVVGFGAGTRATAVLQWSAAAQRYTVATPAHQPAANAHHLLHHHLDQYINTHKDLMSLGVVLRETYAPLLALSRLPTLPQLGLHHVRTQMPTPTFTLLAHSWRKIRVIYAGAYSIEVGIRGGGIVTIRDGSYSKFDRAPIVDEFAPAQGLKTFLSRYVDDSLSARLVAEDDNPPSPMSPMPPGGLRFPAPLTPPQPHTPHSAPVTPHPASPAHQMGGGSFNLTSPPGRRRRRCGRVSCIPHGAVTARRPPRPSPGHHPSPRHHIDHKGPQASSSTSSRSGGRAWGGGAATPLAVSKLEALCTPCEPPPGAPPGPALAPLQRFLACVYMKRTLQRFVNVEEFVNLTLVSVDATSLTFRSDAAGLCARVALHPQHMQSLHLHLTPLPESKEIWSPDDLQVIEKFFEVRVAIAPYRPTALQGWVRWWGAPAAALTSLVAVMRAELAPQVPALWALQWALRIPPAAPPIVPAGQPAVLLAKNKILFFICLTRMDTQLVLPLVYDMQLNVTQLADKQNAQPHLIAVSLHLKRFNEFNQSHSECTLWPAVRDLVTNFTLPAEAGAAPPPP
Length843
PositionTail
OrganismBombyx mori (Silk moth)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Bombycoidea> Bombycidae> Bombycinae> Bombyx.
Aromaticity0.07
Grand average of hydropathy-0.156
Instability index56.60
Isoelectric point9.58
Molecular weight91417.75
Publications
PubMed=19121390

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29299
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.48|      10|      18|     384|     393|       1
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  384-  393 (18.24/12.53)	IRVIYAGAYS
  403-  412 (18.24/12.53)	IVTIRDGSYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     240.02|      51|      52|     486|     537|       2
---------------------------------------------------------------------------
   76-   98 (32.98/ 7.77)	..............LTHGPFT.....PLD.TPGMQP...G............KRKLSS
  460-  503 (63.72/24.47)	PPGGLRFPAP............L.TPPQPhTPHSAPvtpHPA.SPaHQMGGGSFNLTS
  504-  556 (90.43/33.96)	PPGRRRRRCGRVSCIPHGAVTAR.RPPRP.SPGHHPsprHHI.D..HKGPQASSSTSS
  557-  597 (52.89/16.66)	RSGGRAWGGGAATPLAVSKLEALcTPCEP.PPGAPP...GPAlAP.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     109.87|      33|      51|     259|     291|       3
---------------------------------------------------------------------------
  215-  236 (31.29/17.47)	.........Q................GE..RRCVYLQYELGTDAGRTAE
  259-  291 (59.89/40.28)	PAQERESLWQ................GVFIRSYTYRSLVVGFGAGTRAT
  312-  348 (18.69/ 7.42)	PAANAHHLLHhhldqyinthkdlmslGVVLRE.TYAPL...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.55|      11|     784|      46|      56|       4
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   46-   56 (23.93/11.38)	PSPANNNQPPP
  833-  843 (22.62/10.29)	PAEAGAAPPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.98|      38|     549|     109|     177|       6
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  133-  177 (51.35/76.17)	AQELSSRGVSHGgvQGEWSgsaLGMRLVslPLPEGASVAAGSALR
  639-  676 (70.64/30.97)	AAGLCARVALHP..QHMQS...LHLHLT..PLPESKEIWSPDDLQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29299 with Med14 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ARLVAEDDNPPSPMSPMPPGGLRFPAPLTPPQPHTPHSAPVTPHPASPAHQMGGGSFNLTSPPGRRRRRCGRVSCIPHGAVTARRPPRPSPGHHPSPRHHIDHKGPQASSSTSSRSGGRAWGGGAA
443
568










Molecular Recognition Features






MoRF SequenceStartStop




NANANA