<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29283
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MSETAQVSSLPLPPMQYINFYTDENVRRNRAPLPPRPIHDSYSMFGNSFNADDAIIRSLESQGFRRLYPMHFERRRELKKLNHSLLANFLDLLDLLVHCPDSPKRAEKVEDLSLLFIHIHHLLNEFRPHQARETLRVMMELQKRQRVETAARFKKHLDKVQDILQNALQSLPDQNELESNFKVPNELLDQMENNTCNIQKADPCFELDRIMCNVVDNMR |
Length | 219 |
Position | Middle |
Organism | Bombyx mori (Silk moth) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Bombycoidea>
Bombycidae> Bombycinae> Bombyx.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.617 |
Instability index | 54.27 |
Isoelectric point | 6.51 |
Molecular weight | 25820.29 |
Publications | PubMed=19121390
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP29283
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 75.28| 24| 26| 71| 96| 1
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71- 96 (35.86/29.24) HFE..RRRELKKLNHSLLanFLDLLDLL
98- 123 (39.42/25.44) HCPdsPKRAEKVEDLSLL..FIHIHHLL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 76.35| 22| 26| 20| 44| 3
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20- 44 (37.72/29.62) FYTDENVRRNrapLPPRPIHDSYSM
49- 70 (38.63/21.85) FNADDAIIRS...LESQGFRRLYPM
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