<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29272

Description Mediator complex subunit 22
SequenceMSSLPGAGPGSRALPQSKEALLQSYNKRLRDDARSLADNFAEIVKTAKIEEETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAINQRNQQLRALQEECDRKLIALRDEMSVDLYELEEEYYSSSCSLSDATDLPLCEAFWREETAASSPESLSLPLPTANANANALEPSFPVPPGSTPSHTHVNGHGVGPADQA
Length215
PositionHead
OrganismAnolis carolinensis (Green anole) (American chameleon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Lepidosauria> Squamata> Bifurcata> Unidentata> Episquamata> Toxicofera> Iguania> Dactyloidae> Anolis.
Aromaticity0.05
Grand average of hydropathy-0.535
Instability index69.57
Isoelectric point4.68
Molecular weight23557.85
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29272
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.19|      20|      20|     115|     134|       2
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  115-  134 (33.19/26.25)	LQEECDRKLIALRDEMSVDL
  137-  156 (33.99/27.06)	LEEEYYSSSCSLSDATDLPL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29272 with Med22 domain of Kingdom Metazoa
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