<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29244
Description |
Uncharacterized protein |
Sequence | MSSDILTQLQTCYDQLLTQFFSTISYLSQRHPLVAPEPDPNDPFTFPPSNAVTTHTQSQTQTPGASQTASHQPQIQPGPEDTDRAPYPLRPVPPQVFANAQRELAEDLVQKGQQIELLVSRLPGIGASEQQQAEEIRVLAEKVRDMEEKRKAKRKEMQEYVRRLDGVILGMSQSIEELEVNK |
Length | 182 |
Position | Middle |
Organism | Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black yeast) (Wangiella dermatitidis) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Exophiala.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.715 |
Instability index | 73.31 |
Isoelectric point | 5.02 |
Molecular weight | 20492.76 |
Publications | PubMed=24496724
PubMed=28348446
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP29244
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 125.40| 40| 40| 96| 135| 1
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96- 135 (63.95/40.22) VFANAQRELAEDLVQKGQQIELLVSRLPGIGASEQQQAEE
138- 177 (61.45/38.40) VLAEKVRDMEEKRKAKRKEMQEYVRRLDGVILGMSQSIEE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 129.88| 36| 40| 11| 47| 2
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11- 47 (63.10/41.85) TCYDQLLTQfFSTISYLSQRHPLVAPEPDPNDPFTFP
53- 88 (66.78/39.70) TTHTQSQTQ.TPGASQTASHQPQIQPGPEDTDRAPYP
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|