<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29226

Description Uncharacterized protein
SequenceMPHMGGSIREEVEVALHEHRFLVTKLLESLNTASLPPSTITATRLRTVNETFHKVLEKDRELLLAVKKLARHQLAQKELLRVEAEIESKKHKVVQYAAQLRRSQEDIANVLRKHRVVLQNAKHQSKVVLDPRDIVAYAHRIAGTTSAPKEWQPGLPMFGFMPPAPQEHMMRAGVLSRGIVAEIVTQGPEKYTSTAARVKQEGEGSDAIEKLNIPIGLGASDAQIRKQMPPGWKPGDPVDLPLDALLHYMGRSFFTEHGITLPESWKTGDPLPPDAMEILRKKFKLPEKRAPLYDDEVVDDVESLRKKRKLDEGDKADEGTAESDSSSDSSDSDEEAPNTISLSLSSTCRPGNVEKTGSIAKLRQQEAAAPNVASPKGISIKTPGKLPAAQTGGDHSLGLQRRRLSVVSDNKLVDGMAAATIEDVDSSAQALADGTCAVVAFAGLSKKGYAPYNPRKKNQDAMVIKYDNNTQTLLLCVFDGHGEAGDGVSGAIRERFAADLLAHAKFERSGDLQQDAESLRTAIADTLRSVEQAVLRDPSIDTEFSGTTAVVTVVRDNLVVVGNVGDSRITRGFVKLLSPSGPETLGSQELSIDHKPDRPDEKARIISSGGRVFAVEYDDGIDGPPRVWLGHMDVPGLAMSRSLGDAVAHTAGVLSEPEFSTRWLDEHDRCLIVATDGLWEFMSNEECMEIAMGQQDPKLAVDLLIMEANRRWMKEEQVIDDTTIIVAYIDTVGLKDTKTTA
Length741
PositionMiddle
OrganismPhytophthora ramorum (Sudden oak death agent)
KingdomOomycetes
LineageEukaryota> Sar> Stramenopiles> Oomycota> Peronosporales> Peronosporaceae> Phytophthora.
Aromaticity0.04
Grand average of hydropathy-0.398
Instability index48.43
Isoelectric point5.58
Molecular weight80964.81
Publications
PubMed=16946064

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
phosphatase activity	GO:0016791	IEA:InterPro
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29226
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.50|      27|      55|      42|      68|       1
---------------------------------------------------------------------------
   42-   68 (43.07/33.00)	ATRLRTVNETFHKVLEKDRELLLAVKK
   97-  123 (44.43/34.28)	AAQLRRSQEDIANVLRKHRVVLQNAKH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.58|      19|      23|     274|     296|       5
---------------------------------------------------------------------------
  274-  296 (29.25/27.87)	DAMEILRKKFKLPE.KRAplydDE
  299-  318 (29.33/16.53)	DDVESLRKKRKLDEgDKA....DE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.99|      18|      30|     212|     241|       6
---------------------------------------------------------------------------
  221-  241 (31.32/38.79)	DAQIrKQM............PPGWKPGDPvdLP
  243-  272 (29.67/ 9.03)	DALL.HYMgrsfftehgitlPESWKTGDP..LP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.19|      30|      30|     322|     351|       7
---------------------------------------------------------------------------
  322-  351 (50.68/36.86)	ESDSS.SDSSDSDEEAPNTISLSLSSTCRPG
  354-  384 (45.52/32.27)	EKTGSiAKLRQQEAAAPNVASPKGISIKTPG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29226 with Med4 domain of Kingdom Oomycetes


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DDEVVDDVESLRKKRKLDEGDKADEGTAESDSSSDSSDSDEEAPNTISLSLSSTC
2) VEKTGSIAKLRQQEAAAPNVASPKGISIKTPGKLPAAQTGGDHSLGLQR
294
353
348
401










Molecular Recognition Features






MoRF SequenceStartStop




1) MEILRKKFKLP
276
286