Description | Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MEGEGDSRVHFSEVSDPWSSSRHVEVLQALDSVEKKLVTALRTAATAMSLMAPRVSSEESSSLAFNSACTEFLQLVKEIHTELANHIHLVSDYRTFARSTYGAEKDVEISREKVKVVSEQLQTLSRFLEDHYTPEES |
Length | 137 |
Position | Head |
Organism | Phytophthora ramorum (Sudden oak death agent) |
Kingdom | Oomycetes |
Lineage | Eukaryota> Sar> Stramenopiles> Oomycota> Peronosporales> Peronosporaceae> Phytophthora. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.392 |
Instability index | 71.65 |
Isoelectric point | 5.09 |
Molecular weight | 15388.95 |
Publications | PubMed=16946064 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147 |
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP29225 No repeats found |
MoRF Sequence | Start | Stop |
1) DYRTFARSTYGA 2) LMAPR 3) RFLEDHYTPEE 4) SRVHFSEV | 92 50 126 7 | 103 54 136 14 |
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