<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29213

Description Uncharacterized protein
SequenceMGFCLPLSDLDESYKSWARKWSQFEISIQKFGRYPAKLETTRVGLFVNNARKQLADLWPGLAKRCRGLIKAWQKLVEPTTNSSSASTSRNGTPSLVSPAVGGGRRLTPHTPASRRITPGIASERASNLSPSANGSYAPKGSSLLSPGLGMHKSHSVGFDLKDENGGAGGGGARNGKRKQDEPAEPVPGTAPSSIKRAKTTASGLNAAGALTSPAPPATPSLIETRRAAVQSTSDLVAQLTSNLPFRGFEDAAKAHEEKVKREAEDQQLAAALANGGEPAQSPYVFDKKRKYERKKPLGSTPSSAALASQAQASSSTSSTTTVRIVTPPAEGGKGGLVLKLSLSRTTTDTGSLAQQAATPAAAAAPGLQDSKREEKERRKREKKEAALRASKSAPVLAALADEARASTSASASGTSSATAAWLQSQQAAQMTSSSSAASSMDGGGEKKKEKIDWFAMVPSIAELQARVSKDTERRKLLAGMKDAEKAYTLHVGDGRVILALPYIEIEDKPDFLKFNYPDPGRFYAEENFIGGLMERPVHPAPPTPAAAAAGSSTMEYNTLMIKMTTAKIEVSDLSKKMQFALADLREQGQLPAEAPPPVSESAHDNYQYSFLG
Length612
PositionUnknown
OrganismPristionchus pacificus (Parasitic nematode)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Diplogasteromorpha> Diplogasteroidea> Neodiplogasteridae> Pristionchus.
Aromaticity0.05
Grand average of hydropathy-0.526
Instability index56.07
Isoelectric point9.60
Molecular weight64736.10
Publications
PubMed=18806794

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29213
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     477.79|     109|     114|     165|     278|       1
---------------------------------------------------------------------------
   77-  163 (76.67/26.35)	........................EPTTNSSSAST.....SRNGTPSlvSPAVGGGrRLT.PHTPAsrriTPGIASERASNLSpSANGS..YAPKGSSLLSP....GL.GMHKSHSVGFDLKDE..........
  165-  274 (169.95/68.86)	GGAGGGGAR.....NGKRKQdEPAEPVPGTAPSSI.....KRAKTTA..SGLNAAG.ALTSPAPPA....TPSLIETRRAAVQ.STSDL..VAQLTSNLPFR....GFEDAAKAHEEKVKREAEDQQLAAALAN
  275-  390 (113.16/46.57)	...GGEPAQspyvfDKKRKY.ERKKPL.GSTPSSAalasqAQASSST..SSTTTVR.IVTPPAEGG....KGGLV.LKLSLSR.TTTDTgsLAQQAAT.PAAaaapGLQDSKR..EEKERRKREKKE.AALRAS
  404-  501 (118.00/44.76)	RASTSASA......SG.......TSSATAAWLQSQ.....QAAQMTS..SS.SAAS.SMDGGGEKK....KEK.ID.WFAMVP.SIAEL..QARVSKDTERRkllaGMKDAEKAYTLHV....GDGRVILALP.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29213 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AALADEARASTSASASGTSSATAAWLQSQQAAQMTSSSSAASSMDGGG
2) PFRGFEDAAKAHEEKVKREAEDQQLAAALANGGEPAQSPYVFDKKRKYERKKPLGSTPSSAALASQAQASSSTSSTTTVRIVTPPAE
3) TDTGSLAQQAATPAAAAAPGLQDSKREEKERRKREKKEAALRASKSA
4) TTNSSSASTSRNGTPSLVSPAVGGGRRLTPHTPASRRITPGIASERASNLSPSANGSYAPKGSSLLSPGLGMHKSHSVGFDLKDENGGAGGGGARNGKRKQDEPAEPVPGTAPSSIKRAKTTASGLNAAGALTSPAPPATPSLIETRRAAVQSTSDLV
397
244
347
79
444
330
393
236










Molecular Recognition Features






MoRF SequenceStartStop




1) IKRAKT
2) KERRKREKKE
3) QSPYVFDKKRKYERKKPLGS
194
375
280
199
384
299