<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29199

Description Uncharacterized protein
SequenceMTMGSLNPQVKTMEYAVRGPIVIRAVELEKELAHGVPKPFKSVIKANIGDAHAMGQKPITFIRQVLGAVANPALLSSPDLPSDVKNRVETILGGCGGKSAGAYSQSTGVDVIRKHVAEFIQRRDGGAAVDPENVILSGGASESIRNVMKLFINRTGGRKVGFMVPIPQYPLYSATIEEFGLGQVGYFLNEENKWGLDESELERSYNESLKEFDTKVIVIINPGNPTGQVLPRENIEMIIKFAKKHNLFIMADEVYQDNVYAEGSQFHSFKKVLMSMGDPYDKMELASFHSVSKGYMGECGLRGGYVEFANLDPEVFVMFKKMISAKLCSTVLGQAVIDTVVNGPKEGEPSYGQWKKEKDAVLASLKERAVLVEQAYGSIEGITCNPVQGAMYAFPQIHLPEKAIKAAKALNQEPDFFYAMKLLESTGVCIVPGSGFCQKPGTYHFRTTILPQPELMRDMLTRFKSFHEKFISEMSDEEKGDANNEYLAQIYQRKECILWGSIYATNLIDLENRLAGICDPGCTPFHEHEMSFSLKTTQTPDVTLRLRRKFHTETTSSNQWRFRYVGRPEPDPNCPVVVRKVIDSVAHSQNMMEFVKTLGLRLDYEYMAKGKVWTCGAIKIVVSSLKRTKQPGKYEVENLEKMSDSYLIELSVTINDSVDYHPIAKQLKAFSSQLSPLVELQKVEYWVK
Length688
PositionHead
OrganismPristionchus pacificus (Parasitic nematode)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Diplogasteromorpha> Diplogasteroidea> Neodiplogasteridae> Pristionchus.
Aromaticity0.09
Grand average of hydropathy-0.260
Instability index37.54
Isoelectric point6.93
Molecular weight76941.69
Publications
PubMed=18806794

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
hydrolase activity, acting on ester bonds	GO:0016788	IEA:InterPro
pyridoxal phosphate binding	GO:0030170	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
biosynthetic process	GO:0009058	IEA:InterPro
mRNA processing	GO:0006397	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29199
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.48|      38|      53|     187|     225|       1
---------------------------------------------------------------------------
  187-  225 (61.36/44.76)	FLNEENKWGL.DESELERSYNESlKEFDTKVIVIINPGNP
  241-  279 (63.12/41.58)	FAKKHNLFIMaDEVYQDNVYAEG.SQFHSFKKVLMSMGDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.55|      41|      57|      61|     101|       2
---------------------------------------------------------------------------
   61-  101 (69.81/54.94)	FI.RQVLGAVANP.ALLSSPDLPSDVKNRVETILGGCGGKSAG
  119-  161 (60.74/46.69)	FIqRRDGGAAVDPeNVILSGGASESIRNVMKLFINRTGGRKVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.41|      15|      18|      11|      25|       3
---------------------------------------------------------------------------
   11-   25 (26.49/15.05)	KTMEYAVRGPI..VIRA
   30-   46 (21.92/11.33)	KELAHGVPKPFksVIKA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29199 with Med18 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) WRFRYV
560
565