<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29199

Description Uncharacterized protein
SequenceMTMGSLNPQVKTMEYAVRGPIVIRAVELEKELAHGVPKPFKSVIKANIGDAHAMGQKPITFIRQVLGAVANPALLSSPDLPSDVKNRVETILGGCGGKSAGAYSQSTGVDVIRKHVAEFIQRRDGGAAVDPENVILSGGASESIRNVMKLFINRTGGRKVGFMVPIPQYPLYSATIEEFGLGQVGYFLNEENKWGLDESELERSYNESLKEFDTKVIVIINPGNPTGQVLPRENIEMIIKFAKKHNLFIMADEVYQDNVYAEGSQFHSFKKVLMSMGDPYDKMELASFHSVSKGYMGECGLRGGYVEFANLDPEVFVMFKKMISAKLCSTVLGQAVIDTVVNGPKEGEPSYGQWKKEKDAVLASLKERAVLVEQAYGSIEGITCNPVQGAMYAFPQIHLPEKAIKAAKALNQEPDFFYAMKLLESTGVCIVPGSGFCQKPGTYHFRTTILPQPELMRDMLTRFKSFHEKFISEMSDEEKGDANNEYLAQIYQRKECILWGSIYATNLIDLENRLAGICDPGCTPFHEHEMSFSLKTTQTPDVTLRLRRKFHTETTSSNQWRFRYVGRPEPDPNCPVVVRKVIDSVAHSQNMMEFVKTLGLRLDYEYMAKGKVWTCGAIKIVVSSLKRTKQPGKYEVENLEKMSDSYLIELSVTINDSVDYHPIAKQLKAFSSQLSPLVELQKVEYWVK
Length688
PositionHead
OrganismPristionchus pacificus (Parasitic nematode)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Diplogasteromorpha> Diplogasteroidea> Neodiplogasteridae> Pristionchus.
Aromaticity0.09
Grand average of hydropathy-0.260
Instability index37.54
Isoelectric point6.93
Molecular weight76941.69
Publications
PubMed=18806794

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
hydrolase activity, acting on ester bonds	GO:0016788	IEA:InterPro
pyridoxal phosphate binding	GO:0030170	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
biosynthetic process	GO:0009058	IEA:InterPro
mRNA processing	GO:0006397	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP29199
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.48|      38|      53|     187|     225|       1
---------------------------------------------------------------------------
  187-  225 (61.36/44.76)	FLNEENKWGL.DESELERSYNESlKEFDTKVIVIINPGNP
  241-  279 (63.12/41.58)	FAKKHNLFIMaDEVYQDNVYAEG.SQFHSFKKVLMSMGDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.55|      41|      57|      61|     101|       2
---------------------------------------------------------------------------
   61-  101 (69.81/54.94)	FI.RQVLGAVANP.ALLSSPDLPSDVKNRVETILGGCGGKSAG
  119-  161 (60.74/46.69)	FIqRRDGGAAVDPeNVILSGGASESIRNVMKLFINRTGGRKVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.41|      15|      18|      11|      25|       3
---------------------------------------------------------------------------
   11-   25 (26.49/15.05)	KTMEYAVRGPI..VIRA
   30-   46 (21.92/11.33)	KELAHGVPKPFksVIKA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP29199 with Med18 domain of Kingdom Metazoa

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