<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP29194

Description Mediator of RNA polymerase II transcription subunit 15
SequenceMDGDWPSQLFREHVIHRLEPELQRNSRNGPNLPVPGDARQVEEYVFQKCASKDEYMRTIAKVINAINCNSKSAAVPPALPPPANPQLGSAPPPPDPQPTQTAARAAAPAAASAAAVEEDAAGSDRTPQQQRRPRQVLQPPAAQQQPQQQPMHRAPPPQMHNPYAAPQQHQYGQSQPQHSYGSPGMGGPGGGMAGLPGGGLPPLSAAEQIVYDNKLRALSPYIEHLRAKAQQVRAEGSLEGAGKLETMIEVLEGRRRVRLDYLTNLEAWIIKKKEYLLAQSPSTPHGSAGSIMSGLSSDGGGGAISEALSATMMIDHGQGPPPPTGMGGYGPQSGYGMQPPPQQQPQQQHHGMGGGGGWHPQIAGPGAGAGPQSHHLMQPPQQQYGGGGPMHPHVPYRASHALEMARPYPSAHARPTPGHHHAMVGGGGHISGHPGSPFDQGGPSGLSGLSEVATRECRAAADRFDVARMAEERTAPGHVLLRCTMRSRQVPPLRLLVPLSYPQQGAVKVDREEIDLAAFMFDDLQSAVHSRLAMPGLRTITDYLDTWESIVRQWFLAHPLTQGGGPPPVPSYGPPHAAGGPQSSSCGAPHDGPSGPAYGGPPNSFYGGPPGPSYGPPHGVAGAPGPGYGPPHGGGGPHDSAYGGASDTPNQSYDQPPTEDGGGYEDDPFAQYDF
Length674
PositionTail
OrganismPristionchus pacificus (Parasitic nematode)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.688
Instability index69.29
Isoelectric point6.32
Molecular weight70743.84
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP29194
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.75|      10|      24|     566|     575|       1
---------------------------------------------------------------------------
  566-  575 (23.70/ 6.38)	PPPVPSYGPP
  608-  617 (25.78/ 7.80)	GPPGPSYGPP
  622-  631 (23.27/ 6.09)	GAPGPGYGPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     197.37|      42|      45|      91|     135|       2
---------------------------------------------------------------------------
   91-  132 (67.14/13.48)	PPPPDPQPTQTAARAAAPAAASAAAVEEDAAGSD.......RTPQQ....Q...RR
  139-  175 (61.59/13.56)	PPAAQQQPQQQPMHRAPP.....PQMHNPYA...........APQQhqygQ...SQ
  339-  388 (68.64/15.35)	.PPPQQQPQQQH.HGMGGGGGWHPQIAGPGAGAGpqshhlmQPPQQ....QyggGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.52|      31|      45|     190|     222|       3
---------------------------------------------------------------------------
  182-  216 (52.20/22.29)	SPGM.........ggpgGGMAG..........LPG...GGLPPLSAAEQIVYDNK..LR
  219-  277 (25.32/ 9.67)	SPYIehlrakaqqvraeGSLEGagkletmievLEGrrrVRLDYLTNLEAWIIKKKeyLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.68|      31|     332|     299|     329|       7
---------------------------------------------------------------------------
  310-  336 (37.84/10.58)	ATMMIDHGQGP.PPPTGMGGYG.........pqsGYG.......
  517-  545 (36.03/ 9.72)	AAFMFDDLQSAvHSRLAMPGLR...............TITDYLD
  546-  587 (37.80/10.56)	TWESIVRQWFL.AHPLTQGG.GpppvpsygpphaAGGPQSSSCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.25|      12|      16|     643|     654|      15
---------------------------------------------------------------------------
  643-  654 (23.99/10.93)	GGASDTPNQSYD
  662-  673 (25.26/11.87)	GGYEDDPFAQYD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP29194 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AHPLTQGGGPPPVPSYGPPHAAGGPQSSSCGAPHDGPSGPAYGGPPNSFYGGPPGPSYGPPHGVAGAPGPGYGPPHGGGGPHDSAYGGASDTPNQSYDQPPTEDGGGYEDDPFAQYDF
2) INCNSKSAAVPPALPPPANPQLGSAPPPPDPQPTQTAARAAAPAAASAAAVEEDAAGSDRTPQQQRRPRQVLQPPAAQQQPQQQPMHRAPPPQMHNPYAAPQQHQYGQSQPQHSYGSPGMGGPGGGMAGLPGGGLPPLSAA
3) MDGDWPSQLFREHVIHRLEPELQRNSRNGPNLPVPGDARQVEEYVFQ
4) QSPSTPHGSAGSIMSGLSSDGGGGAISEALSATMMIDHGQGPPPPTGMGGYGPQSGYGMQPPPQQQPQQQHHGMGGGGGWHPQIAGPGAGAGPQSHHLMQPPQQQYGGGGPMHPHVPYRASHALEMARPYPSAHARPTPGHHHAMVGGGGHISGHPGSPFDQGGPSGLSGLSEVA
557
66
1
279
674
206
47
453










Molecular Recognition Features






MoRF SequenceStartStop




1) GGYEDDPFAQYDF
662
674